Microsimulation Modeling Effective Health Policies for Colorectal Cancer
MSKCC Principal Investigator
Ann Zauber, PhD
Study Objective
To develop microsimulation population based models for the natural history of colorectal cancer; to determine the optimal best case strategies to reduce the CRC mortality rates in the population; and to use these models to inform health policy
Why Is this Study Important?
Even though we have effective strategies to reduce colorectal cancer (CRC) mortality, CRC is the number two cause of cancer death in the United States. The difficulty is in getting these successful interventions implemented in the general population. The microsimulation modeling can provide guidance to health policy planners in choosing effective policies for intervention.
Who Is Conducting this Study?
The study is being conducted by our investigator, Ann Zauber, in collaboration with Erasmus MC University in Rotterdam. We are part of the Cancer Intervention and Surveillance Modeling Network of the National Cancer Institute.
Contact
Ann Zauber
Selected Publications
- Vogelaar I, van Ballegooijen M, Schrag D, Boer R, Winawer SJ, Habbema JDF, Zauber AG. How much can current interventions reduce colorectal cancer mortality in the US? Mortality projections for scenarios of risk factor modification, screening and treatment. Cancer 2006;107:1624-1633.
- Zauber AG, Lansdorp-Vogelaar I, Knudsen AB, Wilschut J, van Ballegooijen M, Kuntz KM. Evaluating test strategies for colorectal cancer screening: a decision analysis for the U.S. Preventive Services Task Force. Annals of Internal Medicine 2008;149:659-669 PMCID PMC2731975
- Lansdorp-Vogelaar I, van Ballegooijen M, Zauber AG, Boer R, Wilschut J, Habbema JD. At what costs will screening with CT colonography be competitive? A cost-effectiveness approach. Int J Cancer. 2009 Mar 1;124(5):1161-8.
- Lansdorp-Vogelaar I, van Ballegooijen M, Zauber AG, Boer R, Wilschut J, Winawer SJ, Habbema JDF. Individualizing colonoscopy screening by gender and race. Gastrointestinal Endoscopy. 2009 May 23. NIHMSID 129215
