Hodgkin's disease can arise in lymph nodes almost anywhere in the body, and symptoms of the disease depend on its location. If the disease develops in lymph nodes that are close to the skin in the neck, underarms, and groin, symptoms are likely to include a persistent, painless swelling of the nodes. If the disease develops in the chest, symptoms may include cough, shortness of breath, and chest pain. When Hodgkin's disease involves lymph nodes in the pelvis or abdomen, symptoms may include a feeling of fullness or abdominal swelling.
Lymph nodes swell for many reasons, most often as a result of an infection; swollen lymph nodes are usually not caused by Hodgkin's disease. Physicians may treat a patient who has a persistent swelling with antibiotics. If this treatment does not reduce the swelling, the physician may order a biopsy of the swollen node.
Other generalized symptoms of Hodgkin's disease include fever, fatigue, night sweats, unexpected weight loss, and itchy skin. A rare symptom is pain induced by the ingestion of alcohol. Like swollen lymph nodes, these symptoms (except for the last) are associated with a wide range of conditions and illnesses. But if these problems persist, consult a physician.
