Sloan-Kettering Institute
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Eric Lai
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Notch Signaling
Selected Publications
Lai, E. C., F. Roegiers, X. Qin, Y. N. Jan and G. M. Rubin (2005). The ubiquitin ligase Drosophila Mind Bomb promotes Notch signaling by regulating the localization and activity of Serrate and Delta. Development 132: 2319-2332.
Lai, E. C. (2004). Notch signaling: control of cell communication and cell fate. Development 131: 965-973.
Lai, E. C. (2002). Protein degradation: Four E3s for the Notch pathway. Current Biology 12: R74-78.
Lai, E. C., G. A. Deblandre, C. Kintner and G. M. Rubin (2001). Drosophila Neuralized is a ubiquitin ligase that promotes internalization and degradation of Delta. Developmental Cell 1: 783-794.
Lai, E. C. and G. M. Rubin (2001). Neuralized functions cell-autonomously to regulate a subset of Notch-dependent processes during adult Drosophila development. Developmental Biology 231: 217-233.
Lai, E. C. and G. M. Rubin (2001). Neuralized is essential for a subset of Notch pathway-dependent cell fate decisions during Drosophila eye development. Proc. Natl. Acad. Sci. USA. 98: 5637-5642.
©2008 Memorial Sloan-Kettering Cancer Center.