Memorial Sloan-Kettering Cancer Center

Multiple Endocrine Neoplasia

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Multiple endocrine neoplasia (MEN) is a syndrome in which benign or cancerous tumors develop in the endocrine system. Both types of multiple endocrine neoplasia, MEN-1 and MEN-2, are inherited disorders. MEN-1 is most commonly seen in women in their 30s and men in their 40s. People with MEN-1 develop tumors of the parathyroid glands as well as in the pancreas, pituitary gland, adrenal cortex, and thyroid. MEN-2 includes medullary carcinoma of the thyroid gland, pheochromocytomas, and hyperparathyroidism.

Treatment for both types depends on the stage and types of tumors but may include surgery, chemotherapy, and radiation therapy.


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