Also Known As: Mustargen®, nitrogen mustard
Mechlorethamine stops cancer cells from growing by attacking and interfering with DNA, the genetic material in cells.
How It Is Given:
Intravenously (by vein)
Immediate Side Effects (beginning within 24 hours):
- A metallic taste in the mouth can occur while the drug is being administered or shortly afterwards.
- Nausea and vomiting may begin one-half hour after receiving the drug and can last one to two days. However, with antinausea medicine they are less likely.
Early Side Effect (beginning within one week):
- If the medicine leaks out of the vein into the surrounding tissue during administration, severe local skin damage can occur.
Late Side Effects (beginning after one week):
- A temporary decrease in blood cells (white blood cells and platelets) can occur within one to two weeks after treatment.
- Temporary thinning or loss of hair can occur several weeks after each treatment.
- The vein into which the drug was given can darken.
Special Points:
- Take your antinausea medicine as instructed.
- Do not take aspirin, ibuprofen (e.g., Motrin®, Advil®) products containing them, or similar products unless your doctor prescribes them.
- Tell your doctor or nurse if you are taking any other medications, including over-the-counter preparations that do not require a prescription, herbal remedies, vitamins, or dietary supplements. Some of these may interfere with your chemotherapy.
Call Your doctor or Nurse If You Have:
- Nausea or vomiting and are unable to eat or drink for more than 24 hours after receiving the drug.
- Pain, redness, swelling, or blistering at or near the injection site.
- A fever of 100.5° F (38° C) or higher.
- Any unexpected, unexplained problems.
- Any questions or concerns.
