Also Known As: Hydrea®
Hydroxyurea prevents cancer cells from growing by interfering with DNA, the genetic material in cells.
How It Is Given:
Orally (by mouth)
Immediate Side Effect (beginning within 24 hours):
- Nausea, vomiting, diarrhea, and loss of appetite may occur while the drug is being given.
Late Side Effect (beginning after one week):
- A temporary decrease in blood cell counts--white blood cells, red blood cells, and platelets--may occur within one to two weeks after treatment.
Special Points:
- If you are unable to swallow the capsule(s), open the capsule(s) and mix the contents in a glass of water or juice and drink immediately. The contents of the capsule may also be mixed with a small amount of applesauce.
- It is important to drink plenty of fluids while you are taking this medication.
- Taking the medication at bedtime may decrease nausea.
- Do not take aspirin, ibuprofen (e.g., Motrin®, Advil®) or products containing them, unless your doctor prescribes them.
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Tell your doctor or nurse if you are taking any other medications, including, over-the-counter preparations that do not require a prescription, herbal remedies, vitamins, or dietary supplements. Some of these may interfere with your chemotherapy.
Call Your Doctor or Nurse If You:
- Have fever of 100.5° F (38° C) or higher.
- Develop a skin rash or facial redness.
- Have black bowel movements, bruising, or any other signs of bleeding.
- Have excessive nausea and vomiting, and are unable to eat or drink for more than 24 hours after taking the medication.
- Have any unexplained, unexpected problems.
- Have any questions or concerns.
