Also Known As: Leustatin, 2 CDA
Cladribine stops cancer cells from growing by interfering with DNA, the genetic material in cells. The exact mechanism of action is unclear.
How It Is Given:
Intravenously (by vein)
Early Side Effects (beginning within the first week):
- Localized redness at the injection site
- An elevated temperature (low grade) five to seven days after treatment begins
Late Side Effects (beginning after one week):
- A temporary decrease in blood cell counts (red blood cells, white blood cells, and platelets) up to three weeks after treatment
- A decrease in the number of T-cells (a type of white blood cells) resulting in reduced immunity and possible infection
- A feeling of fatigue or tiredness up to two weeks after treatment
- Headache up to two weeks after treatment
- A skin rash up to two weeks after treatment
Special Points:
- If your immunity is considered low, your doctor or nurse may prescribe an antibiotic to help prevent the development of a certain type of pneumonia.
- Talk to your doctor or nurse about contraception.
- Be sure your doctor or nurse is aware of any other medications, including over-the-counter drugs, herbal remedies, and botanicals that you may be taking while receiving this medication. They may interfere with the action of the chemotherapy agent.
Call Your Doctor or Nurse If You:
- Have a fever of 100.5° F (38° C) or higher.
- Experience pain, redness, or swelling near the injection site.
- Have any black bowel movements, bruising, faint red rash, or any other signs of bleeding.
- Have any unexpected or unexplained problems.
- Have any questions or concerns.
