Also Known As: Elspar®
Asparaginase stops cancer cells from using a specific protein they need to live and grow.
How It Is Given:
- Intravenously (by vein)
- Intramuscularly (into muscle)
Immediate Side Effects (beginning within 24 hours):
- Mild nausea and vomiting can occur one to three hours after treatment.
- Loss of appetite can occur and last several days.
- Flushing, a feeling of tightness in the chest, chest or back pain, shortness of breath, fast heart rate, a choking sensation, and a lowering of blood pressure can occur suddenly while the drug is being given. A skin test may be performed before treatment.
Late Side Effects (beginning after one week):
- Flu-like symptoms such as muscle aches, weakness, and fatigue may occur after several treatments.
- Mood changes, lethargy, increased sleepiness, or mild confusion can occur after treatment.
Special Points:
- Do not take aspirin, ibuprofen (e.g., Motrin®, Advil®), or products containing them unless your doctor prescribes them.
- Tell your doctor or nurse if you are taking any other medications, including over-the-counter preparations that do not require a prescription, herbal remedies, vitamins, or dietary supplements. Some of these may interfere with your chemotherapy.
Call Your Doctor or Nurse If You:
- Have persistent nausea or vomiting and are unable to eat or drink for more than 24 hours after receiving the drug.
- Have a fever of 100.5° F (38° C) or higher.
- Experience increased sleepiness or confusion.
- Have any unexplained or unexpected problems.
- Have any questions or concerns.
