Also Known As: Adriamycin®, "Adria"
Doxorubicin prevents cancer cells from growing by attacking and interfering with DNA, the genetic material in cells.
How It Is Given:
Intravenously (by vein). The color of the solution is red.
Immediate Side Effects (beginning within 24 hours):
- Itching, hives, or a red rash can occur at the injection site and along the vein while the drug is being given. This subsides as soon as the injection of the drug is completed. Tell your nurse if you experience pain at the injection site.
- Nausea and vomiting can begin one to three hours after the drug is given and last for 24 to 48 hours.
- Urine can be pink or red in color for as long as 48 hours after the treatment.
Early Side Effect (beginning within one week):
- Mouth sores can develop within one week after you have received the drug.
Late Side Effects (beginning after one week):
- A temporary decrease in blood cell counts (white blood cells and platelets) can occur within 10 to 14 days after each treatment.
- Temporary thinning or loss of hair is common and can occur two to four weeks after each treatment.
- Damage to the heart muscle can occur after a certain dose level is reached. Studies may be done to check heart function.
- Redness of the skin can develop in an area where radiation has previously been given.
Special Points:
- Take your antinausea medication as instructed.
- Protect your skin from overexposure to the sun. Wear protective clothing and use a sunscreen with an SPF of 15 or greater when in the sun.
- Do not take aspirin, ibuprofen (e.g., Motrin®, Advil®), or products containing them unless your doctor prescribes them.
- Tell your doctor or nurse if you are taking any other medications, including over-the-counter preparations that do not require a prescription, herbal remedies, vitamins, or dietary supplements. Some of these may interfere with your chemotherapy.
Call Your Doctor or Nurse If You:
- Have a fever of l00.5°F (38°C) or higher.
- Experience pain, redness, swelling, or blistering near the injection site.
- Develop mouth sores.
- Have black bowel movements, bruising, red spots on your skin, or any other signs of bleeding.
- Have any unexpected or unexplained problems.
- Have any questions or concerns.
