Also Known As: Fludara
Fludarabine works by interfering with the cancer cell's ability to multiply and grow.
How It Is Given:
Intravenously (by vein).
Immediate Side Effect (beginning within 24 hours):
- Mild nausea and vomiting may begin a few hours after receiving the drug.
Early Side Effects (beginning within one week)
- Temporary flu-like symptoms may occur within 48 hours after receiving the drug (fever, chills, malaise).
- A feeling of fatigue or tiredness may occur and last a few days after treatment.
- Diarrhea may develop a few days after treatment but is uncommon.
- Mouth sores can develop one week after receiving the drug.
Late Side Effects (beginning after one week):
- A temporary decrease in blood cell counts (red blood cells, white blood cells and platelets) can occur one to three weeks after treatment.
- Temporary thinning or loss of hair is common and can begin two to three weeks after treatment.
- A skin rash may develop. It is usually mild.
Special Points:
- Do not take aspirin, ibuprofen (e.g., Motrin®, Advil®), products containing them, or similar products as listed on the Common Medicines Containing Aspirin and Nonsteroidal Anti-Inflammatory Drugs fact card unless your doctor prescribes them.
- Tell your doctor or nurse if you are taking any other medications, including over-the-counter preparations that do not require a prescription, herbal remedies, vitamins, or dietary supplements. Some of these may interfere with your chemotherapy.
- Perform mouth care as instructed by your doctor or nurse.
Call Your Doctor or Nurse If You:
- Have a fever of 100.5° F (38° C) or higher.
- Develop mouth sores or a sore throat.
- Have excessive nausea, vomiting, or diarrhea and are unable to eat or drink for more than 24 hours after receiving the drug.
- Develop a cough or shortness of breath.
- Have black bowel movements, bruising, a faint red rash, or any other signs of bleeding.
- Any unexpected or unexplained problems.
- Have any questions or concerns.
