Also Known As: Anti-CD33 monoclonal antibody calicheamicin; CDP-771; CMA-676; hP67.6-calicheamicin; Mylotarg
Gemtuzumab is an anti-CD33 monoclonal antibody. At present, we do not understand exactly how it works against leukemic cells.
How It Is Given:
Intravenously (IV, by vein)
Side Effects:
(Common and potentially life threatening)
- Low blood counts (white blood cells and platelets)
(Others)
- Low blood pressure
- Fatigue
- Seizure (uncommon)
- Nausea and vomiting (possible severe)
- Changes in blood liver values (not permanent)
- Shortness of breath (uncommon)
- Pneumonia (uncommon)
- Fever, chills, and rigors (common)
Special Points:
- Check with your doctor before you have any dental work and use caution when brushing teeth and flossing to prevent bleeding.
- Do not take part in contact sports while on this drug.
- Take special care with anything that could accidentally cause a cut or bruise (shaving, cooking, gardening).
Call Your Doctor or Nurse If You Have:
- Bleeding, bruising, or black tarry stools (call immediately).
- Blood in the urine or stools or a pinpoint red rash on the skin (call immediately).
- Any unexplained problems.
- Any questions or concerns.
