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Also Known As: Interferon, Roferon-A®

Interferon works by enhancing the body's defense mechanisms, slowing abnormal cell growth, and inhibiting the growth of viruses.

How It Is Given:

Subcutaneously (by injection into tissue just under the skin,SQ)

Intramuscularly (by injection into the muscle, IM)

Intravenously (into a vein, IV)

Early Side Effects:

  • While on interferon, you will feel tired.
  • Fever and chills, relieved with acetaminophen (Tylenol®), can occur while taking this medicine.
  • Muscle aches and headaches can occur. They are usually mild and are relieved with acetaminophen.
  • Mild nausea and vomiting

Late Side Effects:

  • Fatigue
  • A decrease in blood counts
  • Headaches
  • Hepatitis
  • A change in mood, especially depression
  • Heart arrhythmias, irregular heart beats
  • Loss of appetite
  • Confusion, but it is rare.
  • Thinning of your hair can occur after taking this medicine for a few weeks, but it is rare. If it does happen, your hair will grow back after the medication is stopped.

Special Points:

  • Do not take any other medications unless they are prescribed by your doctor.
  • Take two acetaminophen before taking interferon and every four hours as needed.
  • Store the medication in the refrigerator, but do not freeze it.
  • Do not shake the medication vial.

Call Your Doctor or Nurse If You Have:

  • A fever of 100.5° F (38° C) or higher after taking acetaminophen.
  • Severe fatigue.
  • Uncontrolled vomiting or diarrhea.
  • Easy bruising or bleeding that does not stop.
  • Numbness or lack of coordination.
  • Difficulty thinking clearly.
  • Blurred vision.
  • Depression.
  • Any unexpected or unexplained problems.
  • Any questions or concerns.
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