Pediatric Brain Tumors: Our Clinical Trials

Through clinical trials, our medical experts evaluate the safety and effectiveness of new therapies and diagnostic tools for brain tumors. Clinical trials can also help our doctors compare the effectiveness of different aspects of your child’s care, or determine the causes of brain tumors.

If your child is eligible to participate in a clinical trial, he or she may have access to new therapies that are not yet available elsewhere. Our clinical research team is highly experienced in selecting children who are most likely to benefit from a particular investigational therapy. They can guide you through the process of choosing the most appropriate clinical trial for your child’s needs.

Here you can find a list of many of Memorial Sloan Kettering’s current clinical trials for pediatric brain tumors. To learn more about a study, choose from the list below.

Showing 16 trials
Titlesort icon Investigator
A Study of Vorinostat (SAHA) plus Isotretinoin and Chemotherapy in Infants and Young Children with Embryonal Tumors of the Central Nervous System
[Protocol 12-191]
Kramer, Kim, MD
A Pilot Study of Functional Imaging for Cerebellar Mutism Syndrome
Newly Diagnosed & Relapsed/Refractory
[Protocol 12-121]
Young, Robert, MD
A Phase III Study of Chemotherapy After Radiation in Young Patients with Newly Diagnosed Ependymoma
[Protocol 11-090]
De Braganca, Kevin, MD
A Phase II Study of Temozolomide plus Irinotecan with or without Bevacizumab in Children with Recurrent or Refractory Medulloblastoma or PNET
[Protocol 11-089]
De Braganca, Kevin, MD
A Phase II Study of Response-Based Radiation Therapy for Patients with Localized Germ Cell Tumors of the Central Nervous System
[Protocol 12-243]
Dunkel, Ira, MD
A Phase II Study of Pegylated Interferon Alfa-2b (PEGIntron) in Children with Inoperable Craniopharyngioma After Prior Therapy
Relapsed/Refractory
[Protocol 14-037]
Khakoo, Yasmin, MD
A Phase II Study of Intrathecal I131-3F8 in Patients with GD2-Expressing Central Nervous System and Leptomeningeal Neoplasms
[Protocol 05-122]
Kramer, Kim, MD
A Phase I/IIA Study of Dabrafenib in Children with Advanced BRAF Mutation-Positive Solid Tumors
[Protocol 13-016]
Pratilas, Christine, MD
A Phase I/II Study of Veliparib (ABT-888) Given with Radiation Therapy and then Given with Temozolomide in Children with Newly Diagnosed Diffuse Pontine Glioma
Newly Diagnosed
[Protocol 12-176]
Gilheeney, Stephen, MD
A Phase I Study of Single Agent Perifosine for Recurrent Pediatric Solid Tumors
[Protocol 08-091]
Dunkel, Ira, MD
A Phase I Study of p28 in Children with Recurrent or Progressive Brain Tumors
Relapsed/Refractory
[Protocol 13-207]
Dunkel, Ira, MD
A Phase I Study of LEE011 in Children and Adolescents with Malignant Rhabdoid Tumors and Neuroblastoma
Relapsed/Refractory
[Protocol 13-164]
Modak, Shakeel, MD
A Phase I Study of Intrathecal Radioimmunotherapy Using 131I-8H9 for Central Nervous System/Leptomeningeal Cancers
[Protocol 03-133]
Kramer, Kim, MD
A Phase I Study of Convection-Enhanced Delivery of 124I-8H9 for Patients with Non-Progressive Diffuse Pontine Gliomas Previously Treated with Radiation Therapy
[Protocol 11-011]
Souweidane, Mark, MD
A Phase I Study of Cabazitaxel in Children and Teens with Persistent Solid Tumors
Relapsed/Refractory
[Protocol 13-021]
Trippett, Tanya, MD
A Phase I Study of AZD6244 in Pediatric Patients with Recurrent or Refractory Low-Grade Glioma (PBTC-029)
Relapsed/Refractory
[Protocol 12-151]
Dunkel, Ira, MD