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Brian H. Kushner, MD

Selected Publications

Kushner BH, Meyers PA. How effective is dose-intensive/myeloablative therapy against Ewing sarcoma/primitive neuroectodermal tumor metastatic to bone or bone marrow? The Memorial Sloan-Kettering experience and a literature review. J Clin Oncol 2001; 19 :870-880

Kushner BH, Heller G, Kramer K, Cheung N-KV. Granulocyte-colony stimulating factor and multiple cycles of strongly myelosuppressive alkylator-based combination chemotherapy in children with neuroblastoma. Cancer 2000; 89 :2122-2130

Kushner BH, Kramer K, Meyers PA, Wollner N, Cheung NK. Pilot study of topotecan and high dose cyclophosphamide for resistant pediatric solid tumors. Med Pediatr Oncol 2000; 35 :468-474

Kushner BH, Kramer K, Cheung N-KV. Oral etoposide for refractory and relapsed neuroblastoma. J Clin Oncol 1999; 17 :3221-3225

Cheung NKV, Kushner BH, Yeh SJ, Larson SM. 3F8 monoclonal antibody treatment of patients with stage IV neuroblastoma: a phase II study. Int J Oncol 1998; 12 :1299-1306

Cheung NKV, Kushner BH, Cheung IY, Canete A, Gerald W, Liu C, Finn R, Yeh SJ, Larson SM. Anti-GD2 antibody treatment of minimal residual stage 4 neuroblastoma diagnosed at more than 1 year of age. J Clin Oncol 1998; 16 :3053-3060

Kushner BH, Heller G, Cheung N-KV, Wollner N, Kramer K, Bajorin D, Polyak T, Meyers PA. High risk of leukemia after short-term dose-intensive chemotherapy in young patients with solid tumors. J Clin Oncol 1998; 16 :3016-3020

Kushner BH, Cheung N-KV, Kramer K, Heller G, Jhanwar JC. Neuroblastoma and treatment-related myelodysplasia/leukemia: The Memorial Sloan-Kettering experience and a literature review. J Clin Oncol 1998; 16 :3880-3889

Kushner BH, LaQuaglia MP, Wollner N, Meyers PA, Lindsley KL, Ghavimi F, Merchant TE, Boulad F, Cheung NKV, Bonilla MA, Crouch G, Kelleher JF, Steinherz PG, Gerald WL. Desmoplastic small round-cell tumor: Prolonged progression-free survival with aggressive multi-modality therapy. J Clin Oncol 1996; 14 :1526-1531

Kushner BH, Cheung NKV, LaQuaglia MP, Ambros PF, Ambros IM, Bonilla MA, Ladanyi M, Gerald WL. INSS stage 1 neuroblastoma: A prospective study and literature review. J Clin Oncol 1996; 14 :2174-2180

Kushner BH, Cheung NKV, LaQuaglia MP, Ambros PF, Ambros IM, Bonilla MA, Gerald WL, Ladanyi M, Gilbert F, Rosenfield NS, Yeh SD. Survival from locally invasive or metastatic neuroblastoma without cytotoxic therapy. J Clin Oncol 1996; 14 :373-381

Kushner BH, Meyers PA, Gerald WL, Healey JH, LaQuaglia MP, Boland P, Wollner N, Casper ES, Aledo A, Heller G, Schwartz GK, Bonilla MA, Lindsley KL, Merchant TE, Rosenfield NS, Abramson SJ, Cheung NKV. Very high-dose short-term chemotherapy for poor-risk peripheral primitive neuroectodermal tumors, including Ewing's sarcoma, in children and young adults. J Clin Oncol 1995; 13 :2796-2804

Kushner BH, LaQuaglia MP, Bonilla MA, Lindsley K, Rosenfield N, Yeh S, Eddy J, Gerald WL, Heller G, Cheung NKV. Highly effective induction therapy for stage 4 neuroblastoma in children over one year of age. J Clin Oncol 1994; 12 :2607-2613

La Quaglia MP, Kushner BH, Heller G, Bonilla MA, Lindsley KL, Cheung NKV. Stage 4 neuroblastoma diagnosed at more than one year of age: Gross total resection and clinical outcome. J Pediatr Surg 1994; 29 :1162-1166

Kushner BH, Cheung NKV. Absolute requirement of CD11/CD18 adhesion molecules, FcRII, and the phosphotidylinositol - linked FcRIII for monoclonal antibody - mediated neutrophil anti-human tumor cytotoxicity. Blood 1992; 79 :1484-1490

Kushner BH, Hadju SI, Gulati SC, Erlandson RA, Exelby PR, Lieberman PH. Extracranial primitive neuroectodermal tumors: The Memorial Sloan-Kettering Cancer Center experience. Cancer 1991; 67 :1825-1829

Kushner BH, Gulati SC, Kwon JH, O'Reilly RJ, Exelby PR, Cheung NKV. High-dose melphalan with 6-hydroxydopamine-purged autologous bone marrow transplantation for poor-risk neuro-blastoma. Cancer 1991; 68 :242-247

Kushner, BH, Cheung NKV. The clinically effective monoclonal antibody 3F8 mediates nonoxidative lysis of human neuroectodermal tumor cells. Cancer Res 1991; 51 :4865-4870

Kushner BH, O'Reilly RJ, Mandell LR, Gulati SC, LaQuaglia M, Cheung NKV. Myeloblative combination chemotherapy without total body irradiation for neuroblastoma. J Clin Oncol 1991; 9 :274-279

Kushner BH, O'Reilly RJ, LaQuaglia M, Cheung NKV. Dose-intensive use of cyclophosphamide in ablation of neuroblastoma. Cancer 1990; 66 :1095-1100

Kushner BH, Gulati SC, O'Reilly RJ, Heller G, Cheung NKV. Autografting with bone marrow exposed to multiple courses of very high dose cyclophosphamide in vivo and to 4-hydroperoxy-cyclophosphamide in vitro. Med Pediatr Oncol 1990; 18 :454-458

Kushner BH, Cheung NKV. GM-CSF enhances 3F8 monoclonal antibody-dependent cellular cytotoxicity against human melanoma and neuroblastoma. Blood 1989; 73 :1936-1941

Kushner BH, Helson L. Coordinated use of sequentially-escalated cyclophosphamide and cell-cycle-specific chemotherapy (the N4SE protocol) for advanced neuroblastoma: Experience with 100 patients. J Clin Oncol 1987; 5 :1746-1751

Kushner BH, Gilbert F, Helson L. Familial neuroblastoma: Case reports, literature review, etiologic considerations. Cancer 1986; 57 :1887-1893

Kushner BH, Hajdu SI, Helson L. Synchronous neuroblastoma and von Recklinghausen's disease: A review of the literature. J Clin Oncol 1985; 3 :117-120

Kushner BH, Helson L. Monozygotic siblings discordant for neuroblastoma: Etiologic implications. J Pediatr 1985; 107 :405-409


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