Antitumor Assessment: Publications

Moroz, MA., Kochetkov, T., Cai, S., Wu, J., Shamis, M., Nair, JS., de Stanchina, E., Serganova, I., Schwartz, GK., Banerjee, D., Bertino, JR., Blasberg, R. (2011). “Imaging colon cancer response following treatment with AZD1152: a preclinical analysis of [18F]fluoro-2-deoxyglucose and 3'-deoxy-3'-[18F]fluorothymidine imaging”. Clin Cancer Res. 17:1099-1110.

Rossi, F., Yozgat, Y., de Stanchina, E., Veach, D., Clarkson, B., Manova, K., Giancotti, FG., Antonescu, CR., Besmer, P. (2010). “Imatinib upregulates compensatory integrin signaling in a mouse model of gastrointestinal stromal tumor and is more effective when combined with dasatinib.” Mol Cancer Res. 8: 1271-1283.

Koppikar, P., Abdel-Wahab, O., Hedvat, C., Marubayashi, S., Patel, J., Goel, A., Kucine, N., Gardner, JR., Combs, AP., Vaddi, K., Haley, PJ., Burn, TC., Rupar, M., Bromberg, JF., Heaney, ML., de Stanchina, E., Fridman, JS., Levine, RL. (2010). “Efficacy of the JAK2 inhibitor INCB16562 in a murine model of MPLW515L-induced thrombocytosis and myelofibrosis” Blood 115:2919-2927.

Lin, H., de Stanchina, E., Zhou, X.K., Hong, F., Seidman, A., Fornier, M., Xiao, WL., Wesa, K., Cassileth, B.R., Cunnningham-Rundles, S. (2010). “Maitake Beta-glucan promotes recovery of Leukocytes and Myeloid cell function in peripheral blood from Paclitaxel hematotoxicity”. Cancer Immun. Immunother. 59:885-897.

Mu, P., Han. YC., Betel, D., Yao, E., Squatrito, M., Ogrodowski, P., de Stanchina, E., D'Andrea, A., Sander, C., Ventura, A. (2009). “Genetic dissection of the MiR17 approximately 92 cluster of microRNAs in Myc-induced B-cell lymphomas”. Genes Dev. 23: 2806-11.

Regales, L., Gong Y., Shen, R., de Stanchina, E., Vivanco, I., Goel, A., Koutcher, J.A., Spassova, M., Ouerfelli, O., Mellinghoff, I.K., Zakowski, M.F., Politi, K.A., Pao, W. (2009). “Dual targeting of EGFR can overcome a major drug resistance mutation in mouse models of EGFR mutant lung cancer”. J. Clin. Invest. 119:3000-3010.

Caldas-Lopes, E., Cerchietti, L., Ahn J.H., Clement, C.C., Robles, A.I., Rodina, A., Moulik, K., Taldone, T., Gozman, A., Guo, Y., Wu, N., de Stanchina, E., White, J., Gross, S.S., Ma, Y, Varticovski, L., Melnick, A., Chiosis, G. (2009). “Hsp90 inhibitor PU-H71, a multimodal inhibitor of malignancy, induces complete responses in triple-negative breast cancer models”. Proc. Natl. Acad. Sci.USA 106: 8368-8673.

Nair , J.S., de Stanchina, E., Schwartz, G.K. (2009). “The Topoisomerase I Poison CPT-11 Enhances the Effect of the Aurora B Kinase Inhibitor AZD1152 Both in vitro and in vivo”. J. Clin. Cancer Res. 15: 2022-2030.

Antczak, C., Kloepping, C., Radu, C., de Stanchina, E., Abramson, D.H., Djaballah. H. “Revisiting Old Drugs as Novel Agents for Retinoblastoma: In vitro and In vivo Antitumor Activity of Cardenolides”(2009). Inves Ophthalmol Vis Sci., 50: 3065-3073.

Real, P.J., Tosello, V., Palomero, V., Castillo, M., Hernando-Monge, E., de Stanchina , E., Sulis, M.L., Barnes, K., Sawai, C., Homminga, I., Meijerink, J., Aifantis, I., Basso, G., Cordon Cardo, C., Ai, W., Ferrando, A. (2009). “Gamma-secretase inhibitors reverse glucocorticoid resistance in T-ALL”. Nature Med. 15: 50-58.

Lin, H., de Stanchina, E., Zhou, X.K., She, Y.H., Hoang, D., Cheung, S. W-Y, Cassileth, B.R.,Cunningham-Rundles, S. (2009). “Maitake Beta-Glucan Enhances Umbilical Cord Blood Stem Cell Transplantation in NOD/SCID Mouse”. Exp. Biol. and Med. 234: 342-353.

He L., He X., Lim L.P., de Stanchina E., Xuan Z., Liang Y., Xue W., Zender L., Ridzon D., Jackson A.L., Linsley P.S., Chen C., Lowe S.W., Cleary M.A., Hannon G.J. (2007). “A microRNA component of the p53 tumor suppressor network”. Nature 447:1130-1134.