My work integrates clinical trial methods as well as health outcomes research. I am involved in clinical trials evaluating the effects of breast cancer treatment (e.g. chemotherapy or tamoxifen) on ovarian reserve in premenopausal women. This type of work will assist in determining the likelihood of infertility from a given treatment regimen and the impact of common therapies on menstruation and future pregnancy. In postmenopausal women, I am evaluating the use of low dose vaginal estrogens to improve vaginal dryness, atrophy, recurrent urinary tract symptoms and sexual dysfunction. As part of my health outcomes research, I am developing methods and instruments to better measure symptoms, such as sexual health. A goal of this work is to develop additional interventions to decrease the burden of treatment on patients.
In addition, I am an active member of the American Society of Clinical Oncology (ASCO) and the International Society for the Study of Women's Sexual Health (ISSWSH). I am also an active member of the survivorship working group for the Multinational Association of Supportive Care in Cancer (MASCC), an international organization devoted to the understanding of side effects in cancer patients.