Center for Cell Engineering: Center for Cell Engineering Sixth Annual Retreat

On January 31, 2013, the Center for Cell Engineering at Memorial Sloan Kettering Cancer Center hosted its sixth annual retreat. In a symposium focusing on regulation of hematopoietic stem cell (HSC) proliferation and HSC expansion, invited investigators presented recent advances in the regulation of HSC expansion in culture and in vivo in cord blood transplant recipients.

Non-cell Autonomous Control of Blood Stem Cell Fate
Peter Zandstra, PhD
McEwen Centre for Regenerative Medicine
University Health Network, Toronto, Ontario

Maintenance of Long-term HSCs Ex Vivo
Peter S. Klein, MD, PhD
Department of Medicine
University of Pennsylvania, Philadelphia, Pennsylvania

Instructive Contribution of the Vascular Niche to Stem Cell Homeostasis
Shahin Rafii, MD
Department of Genetic Medicine
Weill Cornell Medical College, New York, New York

A Potential Global Role for Dipeptidylpepidase 4 (DPP4/CD26) and Its Inhibition in the Regulation of Hematopoiesis and Other Cell Systems Involved in Regenerative Medicine and Cell Engineering
Hal E. Broxmeyer, PhD
Department of Microbiology/Immunology
Indiana University School of Medicine, Indianapolis, Indiana

Double UCB Transplantation as a Model for Hematopoietic Stem Cell Expansion
John Wagner, MD
Department of Pediatrics
University of Minnesota, Minneapolis, Minnesota