Core Facilities

At Memorial Sloan Kettering Cancer Center, a variety of state-of-the-art core facilities provide services and technology to our basic and translational research programs. Our goal is to provide the highest quality of scientific technology in rapid turn-around time, while operating in a cost-effective manner. Memorial Sloan Kettering's core facilities are staffed by research experts in the technologies offered. Education and training is provided in select cores.

For general information regarding core facilities at Memorial Sloan Kettering Cancer Center, please e-mail Diane Tabarini at tabarind@mskcc.org.

We offer the following services:

The Animal Imaging Core provides investigators with unique capabilities for the noninvasive detection, localization, and characterization of primary and metastatic cancer cells in vivo in small animal models.

The Antitumor Assessment Core provides resources, professional and technical expertise, and advisory services related to the evaluation of a wide range of agents with potential antitumor activity.

The Behavioral Research Methods Core assists clinical and population-based investigators with the design, implementation, and execution of research that involves surveys, interviews, and other behavioral-sciences methods.

The Bioinformatics Core provides bioinformatics consultation, training, and resource development. It also supports the high-performance computing resources of the Computational Biology Center.

The Biostatistics Core serves investigators through collaborative research, general consulting, grant preparation support, education, data management, and computing.

The Donald B. and Catherine C. Marron Cell Metabolism Core Laboratory provides technologies and expertise allowing investigators at Memorial Sloan Kettering to measure small molecules in biological samples and characterize the metabolism of cancer cells.

The Center of Comparative Medicine and Pathology is an academically oriented, interdisciplinary center that supports the development, characterization, care, and use of animal models at Memorial Sloan Kettering.

The Electron Microscopy Core prepares, visualizes, and photographs research specimens for investigators.

The Flow Cytometry Core provides investigators with state-of-the-art equipment and support for flow cytometric analysis and high-speed cell sorting.

Pictured: Isabelle Rivière

The Gene Transfer and Somatic Cell Engineering Core develops, validates, and implements procedures critical to gene-transfer-related clinical research.

The Tri-Institutional Genetically Modified Animal Phenotyping Service provides an extensive baseline phenotypic profile of genetically modified animals.

Geoffrey Beene Translational Oncology Staff Members

The Geoffrey Beene Translational Oncology Core takes advantage of the Center’s wealth of tumor samples by extracting, amplifying, and sequencing DNA in an attempt to characterize important genomic features.

The Glassware Washing Core processes cleaned and sterilized laboratory materials, such as glass, plastics, and instruments, through a central administrative office and satellite processing facilities.

The High-Throughput Drug Screening Facility Core provides investigators with access to high-throughput screening of both small molecules and RNAi libraries using modern robotics and custom-built screening data management databases.

The Immune Monitoring Core helps researchers determine immune responses in patients receiving novel immune therapies with the hope that such therapies can move from the clinical trial phase into standard clinical practice.

The Integrated Genomics Operation is a collaborative core facility focused on generating high-quality genomics data for basic, translational, and clinical research projects.

The Investigational Products Core Facility’s mission is to ensure the quality and regulatory compliance of Memorial Sloan Kettering Cancer Center’s clinical trials investigational products and Investigational New Drug applications, and to promote efficiency in our drug development projects, through a combination of advisory, project management, and quality assurance oversight services.

The Media Preparation Core prepares high-quality, chemically-defined tissue culture and bacteriological media necessary for ongoing cell growth research at Memorial Sloan Kettering.

The Molecular Cytogenetics Core supports the cytogenetic analysis of cells from human and research animal sources using a wide range of chromosome analysis techniques.

The Molecular Cytology Core helps researchers identify and master technologies for detecting and analyzing molecules in their natural environment — for example, in cells, tissues, organs, embryos, and tumors.

The Molecular Microbiology Core provides investigators with the ability to characterize the microbiota inhabiting various human and animal environments based on their 16S ribosomal RNA gene sequences.

Pictured: Monoclonal Antibody Core

The Monoclonal Antibody Core provides information and various services to help researchers generate and use monoclonal antibodies in their experiments.

The Mouse Genetics Core supports the use of genetically manipulated mice for in vivo studies of gene function in biological processes that are of interest to investigators.

The Nuclear Magnetic Resonance Core aids researchers in determining the structure of small molecular compounds, with emphasis on drug discovery and synthetic organic chemistry.

The Organic Synthesis Core designs and executes efficient, economical chemical syntheses of entities that are not readily available to Memorial Sloan Kettering researchers.

The Pathology Core is a centralized, comprehensive facility for research involving human tissue. The resource provides professional expertise in pathology, appropriate samples, and tissue-based experimentation.

The Proteomics and Microchemistry Core provides access to state-of-the-art, mass spectrometry based protein analysis technology. Core services include experimental design consultation, gel band protein ID, post translational modification analysis, SILAC, data analysis, and peptide synthesis.

The Radiation Core provides two animal irradiators and two cell/tissue irradiators for use in research.

Pictured: Jason Lewis

The Radiochemistry & Molecular Imaging Probes Core provides researchers with radionuclides and helps incorporate them into radiolabeled pharmaceuticals and radiolabeled antibodies for both basic research investigations and patient formulations.

The Research Engineering Lab Core provides technical support and development of specialized instrumentation and equipment for researchers.

The Research Pharmacy develops, procures, and validates the preparation and packaging of investigational drugs for clinical use.

The RNAi Core is supports all Memorial Sloan Kettering investigators with resources and tools related to RNA interference technologies.

The Stem Cell Research Core expands, characterizes, and distributes non-NIH approved human embryonic stem cells isolated at the Weill Cornell Medical College and Rockefeller University derivation core facilities.

The Tetramer Core produces human and mouse MHC class I tetramers with a variety of alleles for use by Memorial Sloan Kettering investigators.

The Web Survey Core creates online surveys for capturing data in Memorial Sloan Kettering studies or as part of standard care.

The X-ray Crystallography Core serves structural biologists as well as other researchers who use x-ray crystallography in their research.

Animal Use & Care Information

Animal use within the Center is overseen by the Institutional Animal Care and Use Committee.