Biostatistics: Genomic Data Analysis Journal Club

A process in which anything complex is separated into simple or less complex parts.

The science of collecting and analyzing biologic or health data using statistical methods. Biostatistics may be used to help learn the possible causes of a cancer or how often a cancer occurs in a certain group of people. Also called biometrics and biometry.

A term for diseases in which abnormal cells divide without control and can invade nearby tissues. Cancer cells can also spread to other parts of the body through the blood and lymph systems. There are several main types of cancer. Carcinoma is a cancer that begins in the skin or in tissues that line or cover internal organs. Sarcoma is a cancer that begins in bone, cartilage, fat, muscle, blood vessels, or other connective or supportive tissue. Leukemia is a cancer that starts in blood-forming tissue such as the bone marrow, and causes large numbers of abnormal blood cells to be produced and enter the blood. Lymphoma and multiple myeloma are cancers that begin in the cells of the immune system. Central nervous system cancers are cancers that begin in the tissues of the brain and spinal cord. Also called malignancy.

The study of the patterns, causes, and control of disease in groups of people.

The functional and physical unit of heredity passed from parent to offspring. Genes are pieces of DNA, and most genes contain the information for making a specific protein.

The study of genes and heredity. Heredity is the passing of genetic information and traits (such as eye color and an increased chance of getting a certain disease) from parents to offspring.

A laboratory tool used to analyze large numbers of genes or proteins at one time. In a microarray, biologic molecules such as DNA, RNA, or protein are placed in a pattern onto a surface such as a glass slide. Other substances are added to these slides to detect specific patterns of molecules. Microarrays are being used to help diagnose diseases, such as cancer, and to develop treatments for them.

A legal document in which a person states what is to be done with his or her property after death, who is to carry out the terms of the will, and who is to care for any minor children.