Jennifer Brooks, PhD

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Dr. Brooks is a cancer epidemiologist with a background in the basic sciences (molecular biology, toxicology and nutrition). Her research interests are focused on the genetic and epigenetic epidemiology of breast cancer risk and response to treatment. Specifically, she is interested in investigating how patient characteristics, genetic and epigenetic factors interact with breast cancer treatments to influence risk of disease progression, recurrence and risk of second primary breast cancers. She is also interested in the development of methods of monitoring treatment response. Dr. Brooks has been working with Dr. Bernstein (PI of the Women’s Environmental Cancer and Radiation Epidemiology (WECARE) Study) to investigate the genetic epidemiology of second primary breast cancer including the pharmacogenomics of treatment response and subsequent risk of second breast cancers. Dr. Brooks is also working with Drs. Bernstein and Pike, and investigators in the Department of Radiology at MSKCC to examine the potential of breast tissue characteristics on MRI as risk factors of breast cancer and as indicators of response to treatment.

Publications by Jennifer Brooks

Brooks JD, Zeleniuch-Jacquotte A, Cairns P. DNA methylation analysis for the detection of breast cancer. Cancer Causes Control, 2009; 20(9):1539-50.

King V, Brooks JD, Reiner AS, Bernstein JL, Pike MC, Morris EA. Association between background parenchymal enhancement on breast MRI and breast cancer risk. Radiology. 2011; 260(1):50-66.

Brooks JD, John EM, Mellemkjær L, Reiner AS. Malone KE, Lynch CF, Figueiredo JC, Haile RW, Shore RE, The WECARE Study Collaborative Group, Bernstein JL, Bernstein L. Body mass index and risk of second primary breast cancer:  The WECARE Study. Breast Cancer Res Treat. 2012; 131(2):571-580. PMCID: PMC3251700

Brooks JD, Teraoka SN, Reiner AS, Satagopan JM, Bernstein L, Thomas DC, Capanu M, Stovall M, Smith SA, Wei S, Shore RE, Boice JD Jr, Lynch CF, Mellemkjær L, Malone, KE, Liang X, The WECARE Study Collaborative Group, Haile RW, Concannon P, Bernstein JL. Variants in activators and downstream targets of ATM, radiation exposure and contralateral breast cancer risk in the WECARE Study. Hum Mutat. 2012;33(1):158-64. PMCID: PMC3240722

Brooks JD, Boice JD, Jr, Stovall M, Reiner AS, Bernstein L, John EM, Lynch CF, Mellemkjær L, Knight JA, Thomas DC, Haile RW, Smith SA, Capanu C, The WECARE Collaborative Group, Bernstein JL, Shore RE. Reproductive status at first diagnosis influences risk of radiation-induced second primary contralateral breast cancer in The WECARE Study. Int J Radiat Oncol Biol Phys., In press.