Alan Hanash is an Assistant Member of Memorial Sloan Kettering and an Attending Physician on the Adult Bone Marrow Transplant Service in the Department of Medicine. Dr. Hanash’s research focuses on the immunology of hematopoietic transplantation and immune-mediated mechanisms of tissue damage and regeneration.

Publications

Geiger TL, Abt MC, Gasteiger G, Firth MA, O’Connor MH, Geary CD, O’Sullivan TE, van den Brink MR, Pamer EG, Hanash AM, Sun JC. Nfil3 is crucial for development of innate lymphoid cells and host protection against intestinal pathogens. J Expo Md. 2014 Aug 25; 211(9): 1723-31.

Hanash AM, Kappel LW, Yim NL, Nejat RA, Goldberg GL, Smith OM, Rao UK, Dykstra L, Na IK, Holland AM, Liu C, Murphy GF, Leonard WJ, Heller G, van den Brink MR. Abrogation of donor T cell IL-21 signaling leads to tissue-specific modulation of immunity and separation of GVHD from GVL. Blood. 2011 Jul 14;118(2):446-55.

Hanash AM. MataHari reveals secrets of GVHD. Blood. 2012 Apr 19;119(16):3656-7.

Dudakov JA, Hanash AM, Jenq RR, Young LF, Ghosh A, Singer NV, West ML, Smith OM, Holland AM, Tsai JJ, Boyd RL, van den Brink MR. IL-22 drives endogenous thymic regeneration in mice. Science. 2012 Apr 6;336(6077):91-5. Accompanied by journal commentary: Bhandoola A, Artis D. Rebuilding the thymus.Science 2012 Apr 6;336(6077):40-1.

Hanash AM, Dudakov JA, Hua G, O’Connor MH, Young LF, Singer NV, West ML, Jenq RR, Holland AM, Kappel LW, Ghosh A, Tsai JJ, Rao UK, Yim NL, Smith OM, Velardi E, Liu C, Fouser LA, Kolesnick R, Blazar BR, van den Brink MRM. Interleukin-22 protects intestinal stem cells from immune-mediated tissue damage and regulates sensitivity to graft vs. host disease. Immunity. 2012 Aug 24;37(2):339-50. Accompanied by journal commentary: Diefenbach A. Interleukin-22, the guardian of the intestinal stem cell niche? Immunity. 2012 Aug 24;37(2):196-8.

Laboratory phone:
646-888-3437
View Alan M. Hanash’s physician profile.
Selected Achievements

Amy Strelzer Manasevit Research Program Scholar (2014)

ASH Outstanding Abstract Achievement Award for Anna Mertelsmann (2013)

ASH Scholar Award for Junior Faculty (2012)

ASBMT New Investigator Award (2011)