Education & Training
Postdoctoral Research Fellow, Developmental Biology Program, Sloan-Kettering Institute (lab of Kat Hadjantonakis)
PhD degree in microbiology and immunology, Temple University School of Medicine, Philadelphia, PA (lab of Patrick J. Piggot)
Thesis title: “Twin spore formation within one mother cell by Bacillus subtilis”
BS degree in molecular biology and genetics, Democritus University of Thrace, Greece
My interests are to understand how cell fate decisions are made, and in particular how changes in gene expression influence fate choices during development. As a graduate student, my studies are focused on understanding how gene expression regulates cell fate in individual bacterial cells during the process of Bacillus subtilis sporulation, which is considered a model for prokaryotic development and cellular differentiation.
My current work continues to focus on understanding how cell fate is specified, albeit in the mouse as a mammalian model system. Live imaging is an essential tool to observe how fate decisions are made in living organisms and in live stem cell cultures. I am currently generating various fluorescent reporter expressing mouse strains in order to image live cells in developing pre-implantation mouse embryos and embryo-derived stem cells.
The central goal of my ongoing studies is to determine how gene expression might influence the decision a stem cell or lineage progenitor makes to differentiate or self-renew.