Nanotechnology offers some of its greatest potential contributions in the precise control of molecular binding events and the transduction of binding phenomena. My lab is committed to employing this potential for two crucial pursuits: the early detection of cancer, and the innovative treatment of metastatic disease.


DA Heller, Y Levi, JM Pelet, JC Doloff, J Wallas, GW Pratt, S Jiang, G Sahay, A Schroeder, JE Schroeder, Y Chyan, C Zurenko, W Querbes, M Manzano, DS Kohane, R Langer, DG Anderson. Modular ‘Click-in-Emulsion’ Bone-Targeted Nanogels. Advanced Materials 25 (2013) 1449-1454.

JW Kang, FT Nguyen, N Lue, RR Dasari, DA Heller. Measuring Uptake Dynamics of Multiple, Identifiable Carbon Nanotube Species via High-Speed Confocal Raman Imaging of Live Cells. Nano Letters 12 (2012) 6170-6174.

DA Heller, GW Pratt, J Zhang, N Nair, AJ Hansborough, AA Boghossian, NF Reuel, PW Barone, MS Strano. Peptide Secondary Structure Modulates Single-Walled Carbon Nanotube Fluorescence as a Chaperone Sensor for Nitroaromatics. Proceedings of the National Academy of Sciences 108 (2011) 8544-8549.

DA Heller, H Jin, BM Martinez, D Patel, BM Miller, T-K Yeung, PV Jena, C Höbartner, T Ha, SK Silverman, MS Strano. Multi-modal optical sensing and analyte specificity via singlewalled carbon nanotubes. Nature Nanotechnology 4 (2009) 114-120.

DA Heller, ES Jeng, T Yeung, BM Martinez, AE Moll, JB Gastala, MS Strano. Optical Detection of DNA Conformational Polymorphism on Single-Walled Carbon Nanotubes. Science 311 (2006) 508-511.

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Selected Achievements

NIH Director’s New Innovator Award (2012)

Damon Runyon Cancer Research Foundation Postdoctoral Fellowship (2010)

Beckman Institute Graduate Fellowship (2006)