Synthesis of Complex Glycoconjugate Adjuvants for Anti-Cancer and Anti-Viral Vaccine Therapies

The development of therapeutic vaccines often includes the use of synthetic small molecule antigen constructs to elicit immune response.

Development of New Carbohydrate Coupling Reactions

Immunity, cell growth, cell-cell communication and inflammation are among the numerous biological processes influenced by complex carbohydrates.

Total Synthesis of Complex Bioactive Alkaloids

Complex alkaloid natural products have exhibited a wide array of biological activities including, inter alia, antitumor, antiviral, antibacterial, and antifungal properties.

Site-Selective Carbohydrate-Peptide Conjugation

Biological roles of proteins are often determined by their post-translational modifications, which result in the introduction of various functionalities such as carbohydrates and lipids.