Sirkka Moilanen, PhD

Graduate Student (2002 - 2007)
Sirkka Moilanen

Postdoctoral Fellow with Prof. James S. Panek
Department of Chemistry
Boston University

Frank L. Horsfall, Jr. Fellow, 2006–2007

PhD, Cornell University, 2007
Tri-Institutional Training Program in Chemical Biology

BS, Case Western Reserve University, 2001

Thesis: Synthesis of a Structurally and Stereochemically Diverse Spiroketal Library Using Novel Stereoselective Spirocyclizations of C1-Substituted Glycal Epoxides, May 14, 2007

Publications

  1. Stereocontrolled synthesis of spiroketals via Ti(Oi-Pr)4-mediated kinetic spirocyclization of glycal epoxides with retention of configuration.
    Moilanen, S. B.; Potuzak, J. S.; Tan, D. S.* J. Am. Chem. Soc. 2006, 128, 1792–1793.
    Abstract | PubMed | PMC ]
    (Highlighted in Nature )
  2. Stereocontrolled synthesis of spiroketals via a remarkable methanol-induced kinetic spirocyclization reaction.
    Potuzak, J. S.; Moilanen, S. B.; Tan, D. S.* J. Am. Chem. Soc. 2005, 127, 13796–13797.
    Abstract | PubMed  ]
  3. Enantioselective synthesis of erythro-4-deoxyglycals as scaffolds for target- and diversity-oriented synthesis: New insights into glycal reactivity.
    Moilanen, S. B.; Tan, D. S.* Org. Biomol. Chem. 2005, 3, 798–803.
    Abstract | PubMed ]
  4. Discovery and applications of small molecule probes for studying biological processes.
    Potuzak, J. S.; Moilanen, S. B.; Tan, D. S.* Biotechnol. Genet. Eng. Rev. 2004, 21, 11–78.
    TOC | PDF | PubMed ]
  5. In vitro stability of α-helical peptide nucleic acids (αPNAs).
    Garner, P.*; Sherry, B.; Moilanen, S.; Huang, Y. Bioorg. Med. Chem. Lett. 2001, 11, 2315–2317.
    Abstract | PubMed ]

News Articles

09/01/2006
27th Annual Convocation Ceremony
MSKCC Center News
Sirkka Moilanen was awarded a Frank L. Horsfall, Jr. Fellowship for 2006-2007. [Full text]

02/02/2006
Chemistry: Order of the rings
Nature
One of the great challenges in organic chemistry is developing novel ways to synthesize complex structures. The best reactions work for a range of chemical substrates, and give high yields. By these criteria, a reaction, discovered by Derek Tan of the Memorial Sloan Kettering Cancer Center in New York and his co-workers is near ideal. [Full text]