Gabriela Chiosis: Research Fellow

Memorial Sloan-Kettering Cancer Center is located in New York, in Manhattan’s Upper East Side, adjacent to the Cornell University Weill Medical College and the Rockefeller University. This rich scientific environment provides many unique and unparalleled research training opportunities.

A postdoctoral fellow position is available immediately to study the role of Hsp90 and Hsp70 chaperones in malignant transformation. The fellow will investigate mechanisms associated with Hsp-regulation of malignancy and will design rational strategies for the clinical translation of Hsp90 and Hsp70 inhibitors to the treatment of cancers. These efforts will be conducted in collaboration with scientists at Weill Cornell Medical College.

The fellow will join a multidisciplinary team operating at the interface of chemistry, biology and medicine. The team’s efforts focus on understanding mechanisms associated with regulation of pathogenic systems by molecular chaperones (Rodina et al. Nat Chem Biol 2007, Luo et al. PNAS 2007, Caldas et al. PNAS 2009, Cerchietti et al. Nat Med 2009, Marubayashi et al. JCI 2010). The ultimate goal of the team is to translate these findings into novel treatments for neurodegenerative diseases and cancers.

The successful candidate will:

• One to five years of postdoctoral experience
• Demonstrated competence and experience in the biology of cancer
• Demonstrated ability to work independently and lead projects while also collaborating and assisting the group achieve its research goals

Essential Requirements:

• A strong desire to impact cancers
• Creativity in problem solving and a team spirit
• Experience with handling mice
• Knowledge of standard molecular and cell biology methods
• Good communication/written skills
• Passion for science, and flexibility to work some evenings and weekends
• Ability to work towards defined goals in an efficient, safe and scientifically sound manner.

Knowledge of proteomics techniques is a plus.