Jacqueline Bromberg: Publications

Bromberg, JF and Wang, TC. (2009) Inflammation and Cancer: IL-6 and STAT3 Complete the Link, Cancer Cell Feb 3;15 (2):79-80.

de la Iglesia N, Konopka G, Lim KL, Nutt CL, Bromberg JF, Frank DA, Mischel PS, Louis DN, Bonni A. J. (2008) Deregulation of a STAT3-interleukin 8 signaling pathway promotes human glioblastoma cell proliferation and invasiveness. Journal of Neuroscience. June 4; 28(23): 5870-8.

Dickler MN, Rugo HS, Eberle CA, Brogi E, Caravelli JF, Panageas KS, Boyd J, Yeh B, Lake DE, Dang CT, Gilewski TA, Bromberg JF, Seidman AD, D'Andrea GM, Moasser MM, Melisko M, Park JW, Dancey J, Norton L, Hudis CA. A phase II trial of erlotinib in combination with bevacizumab in patients with metastatic breast cancer. Clin Cancer Res. 2008 Dec 1;14(23):7878-83.

Gao, S., Mark,K., Pao, W., Motoi, N., Gerald, W., Travis, W., Bornmann, W., Veach, D., Clarkson, B., Bromberg, JF (2007) Kinase domain activating mutations of the EGFR mediate production of IL-6 leading to activation of the gp130/Jak/Stat3 pathway in lung adenocarcinomas. Journal of Clinical Investigation. Dec 16, 117:3846-3856.

Berishaj, M, Gao, S., Leslie, K., Al-Ahmadie, H., Gerald, W., Bornmann, W., Bromberg, JF (2007). Stat3 is tyrosine phosphorylated through the IL-6/gp130/Jak pathway in breast cancer. Breast Cancer Research May;9(3) 332-38.

Azare, J, Leslie, K, Al-Ahmadie, H., Gerald, W, Weinreb, PH, Violette, SM, Bromberg, JF (2007). Constitutively activated Stat3 induces tumorigenesis and enhances cell motility of prostate epithelial cells through Integrin beta6. Molecular and Cellular Biology Jun;27(12):4444-53.

Fornier MN, Seidman AD, Lake D, D'Andrea G, Bromberg J, Robson M, VanPoznak C, Panageas KS, Atienza M, Norton L, Hudis C. (2007) Increased dose density is feasible: a pilot study of adjuvant epirubicin and cyclophosphamide followed by paclitaxel, at 10- or 11-day intervals with filgrastim support in women with breast cancer. Clin Cancer Res. Jan 1;13(1):223-7.

Pedranzini L, Dechow T, Berishaj M, Azare J, Zhou P, Comenzo, R, Bornmann W, Bromberg, J. (2006) Pyridone 6, a pan-JAK inhibitor, induces growth inhibition of multiple myeloma cells. Cancer Research:Oct 1;66(19):9714-21.

Leslie K, Lang C, Devgan G, Azare J, Berishaj M, Gerald W, Bae P, Paz K, Darnell J, Albanese C Sakamaki T Pestell R and Bromberg J. (2006) Cyclin D1 is transcriptionally regulated by and required for transformation by activated signal transducer and activator of transcription 3. Cancer Research: 66(5) 2544-52.

Gao, P., Bromberg, J. (2006) Touched and Moved by STAT3. Sci STKE. Jul 11: (343):pe30.

Pedranzini L, Leitch A, Bromberg J. (2004) Stat3 is required for the development of skin cancer. J Clin Invest. 114(5):619-22.

Dechow T, Pedranzini L. Leitch A., Gerald W, Linkov I, Bromberg, J. (2004) Requirement of MMP-9 for the Transformation of Human Mammary Epithelial Cells by Stat3-C. Proc Natl Acad Sci U S A Jul 20;101(29):10602-7.