Hsieh J.J.-D., Hayward, S.D. 1995. Masking of the CBF1/RBPJk Transciptional Repression Domain by Epstein-Barr Virus EBNA2. Science. 268:560-563.
Hsieh J.J.-D., Henkel T., Salmon P., Robey E, Peterson M.G., Hayward S.D. 1996. Truncated Mammalian Notch1 Activates CBF1/RBPJk Repressed Genes by a Mechanism Resembling that of Epstein-Barr Virus EBNA2. Mol. Cell. Biol. 16:952-959.
Hsieh J.J.-D., Nofziger D.E., Weinmaster G., Hayward S.D. 1997. Epstein-Barr Virus Immortalization: Notch2 Interacts with CBF1 and Blocks Differentiation. J. Virol. 71:1938-1945.
Hsieh J.J.-D., Zhou S., Chen L., Hayward S.D. 1999. CIR, A Corepressor Linking the DNA Binding Factor CBF1 to the Histone Deacetylase Complex. Proc. Natl. Acad. Sci. USA 9:23-28.
Hsieh J.J.-D., Ernst P., Erdjment-Bromage H., Tempst P., Korsmeyer S.J. 2003. Proteolytic Cleavage of MLL Generates a Complex of N-terminal and C-terminal Fragments that Confers Protein Stability and Subnuclear Localization. Mol. Cell. Biol. 23:186-194.
Hsieh J.J.-D., Cheng E.H., Korsmeyer S.J. 2003. Taspase1: a Threonine Aspartase Required for MLL Cleavage and Proper HOX Gene Expression. Cell 115, 293-303.
Zhou H., Spicuglia S., Hsieh J.J.-D., Mitsiou D.J., Hoiby T., Veenstra G.J., Korsmeyer S.J., Stunnenberg H.G. 2006. Uncleaved TFIIA is a Substrate for Taspase 1 and Active in Transcription. Mol. Cell. Biol. 26(7):2728-35.
Takeda S., Chen D.Y., Westergard T.D., Fisher J.K., Rubens J.A., Sasagawa S., Kan J.T., Korsmeyer S.J., Cheng E.H.-Y., Hsieh J.J.-D. 2006. Proteolysis of MLL Family Proteins is Essential for Taspase1-Orchestrated Cell Cycle Progression. Genes & Development, 20, 2397-2409.
Capotosti F., Hsieh J.J.-D., Herr W. 2007. Species Selectivity of Mixed Lineage Leukemia/Trithorax and HCF proteolytic Maturation Pathways. Mol. Cell. Biol. 27(20), 7063-72.
Liu H., Cheng E.H.-Y., Hsieh J.J.-D. 2007. Bimodal Degradation of MLL by SCFSkp2 and APCCdc20 Assures Cell Cycle Execution: a Critical Regulatory Circuit Lost in Leukemogenic MLL-Fusions. Genes & Development, 21(19), 2385-98.
Hyllus D., Stein C., Schnabel K., Schiltz E., Imhof A., Dou Y., Hsieh J.J.-D., Bauer U. 2007. PRMT6-Mediated Methylation of R2 in Histone H3 Antagonizes H3 K4 Trimethylation. Genes & Development, 21(24), 3369-3380.
Lee J.T., Chen D.Y., Yang Z., Ramos A.D., Hsieh J.J.-D., Bogyo M. 2009. Design, syntheses, and evaluation of Taspase1 inhibitors. Bioorg Med Chem Lett, 19(17), 5086-90.
Chen D.Y., Liu H., Takeda S., Tu H., Sasagawa S, Van Tine B., Lu D., Cheng E.H.-Y., Hsieh J.J.-D. 2010. Taspase1 Functions as a Non-oncogene Addiction Protease that Coordinates Cancer Cell Proliferation and Apoptosis. Cancer Research, 70(13), 5358-67.
Liu H., Takeda S., Kumar R., Westergard T.D., Brown E.J., Pandita T., Cheng E.H.-Y., Hsieh J.J.-D. 2010. Phosphorylation of MLL by ATR is Required for Execution of Mammalian S Phase Checkpoint. Nature. 467(7313):343-6.
Ren D., Tu H., Kim H., Wang G.X., Bean G.R., Takeuchi O., Jeffers J.R., Zambetti G.P., Hsieh J.J.-D., Cheng, E.H.-Y. BID, BIM, and PUMA Are Essential for Activation of the BAX- and BAK-Dependent Cell Death Program. Science 2010; 330:1390-3.
