Huse, J.T., Pijak, D.S., Leslie, G.J., Lee, V.M.-Y, Doms, R.W. “Maturation and Endosomal Targeting of ß-Site Amyloid Precursor Protein-cleaving Enzyme: The Alzheimer's Disease ß-Secretase”. (2000) J Biol Chem 2000;275:33729-33737.

Huse, J.T., Liu, K., Pijak, D.S., Carlin, D., Lee, V.M.-Y., Doms, R.W. “ß-Secretase Processing in the Trans-Golgi Network Preferentially Generates Truncated Amyloid Species That Accumulate in Alzheimer’s Disease Brain”. J Biol Chem 2002;277:16278-16284.

Huse, J.T., Byant, D., Yang, Y., Pijak, D.S., D’Souza, I., Lah, J.J., Lee, V.M.-Y., Doms, R.W., Cook, D.G. “Endoproteolysis of ß-Secretase (BACE) Within its Catalytic Domain: A Potential Mechanism for Regulation”. J Biol Chem 2003;278:17141-17149.

Schessl, J., Medne, L., Hu, Y., Brown, M.J., Huse, J.T., Torigian, D.A., Jungbluth, H., Goebel, H.H., Bonnemann, C.G. “MRI in DNM2-related centronuclear myopathy: Evidence for highly selective muscle involvement”. Neuromuscul Disord 2006;12:28-32.

Chen, H.I., Burnett, M.G., Huse, J.T., Lusting, R.A., Bagley, L.J., Zager, E.L. “Recurrent delayed cerebral necrosis with aggressive characteristics after radiosurgical treatment of an arteriovenous malformation”. J Neurosurg 2006;105:455-460.

Cardillo, S., Huse, J.T., Iqbal, N. “Diabetic muscle infarction of the forearm in a patient with longstanding type I diabetes”. Endocr Pract 2006;12:188-192.

Elmariah, S.B., Huse, J., LeRoux, P., Lustig, R.A. “Multicentric glioblastoma multiforme in a patient with BRCA1 invasive breast cancer”. Breast J 2006;12:470-474.

Huse, J.T., Pasha, T.L., Zhang, P.J. “D2-40 Functions as an effective chondroid marker distinguishing true chondroid tumors from chordoma”. Acta Neuropathol 2006;113:87-94.

Whitmore, R.G., Krejza, J., Kapoor, G.S., Huse, J.T., Woo, J., Bloom, S., Wolf, R.L., Judy, K., Rosenfeld, M., Biegel, J.A., Melhem, E.R., O’Rourke, D.M. “Prediction of oligodendroglial tumor subtype and grade using magnetic resonance perfusion-weighted imaging.” J Neurosurg 2007;107:600-609.

Gasparetto, E.L., Pawlak, M.A., Patel, S.H.,  Huse, J.T., Woo, J.H., Krejza, J., Rosenfeld, M.R., O’Rourke, D.M., Lustig, R., Melhem, E.R., Wolf, R.L. “Posttreatment recurrence of malignant brain neoplasm: accuracy of relative cerebral blood volume fraction in discriminating low from high malignant histologic volume fraction”. Radiology 2009; 250, 887-896.

Perry, A., Miller, C. R., Gujrati, M., Scheithauer, B.W., Jost, S.C., Raghavan, R., Qian, J., Cochran, E.J., Huse, J.T., Holland, E.C., Burger, P.C., Rosenblum, M.K. “Malignant Gliomas with Neuroblastic (PNET-like) Components (GBM-PNET): A Clinicopathologic and Genetic Study of 52 Cases”. Brain Pathol 2009; 19: 81-90.

Bleau, A.-M., Hambardzumyan, D., Ozawa, T., Fomchenko, E.I., Huse, J.T., Brennan, C.W., Holland, E.C. “PTEN/PI3K/Akt pathway regulates the side population phenotype and ABCG2 activity in glioma tumor stem-like cells”. Cell Stem Cell 2009; 4: 226-235.

Huse, J.T., Brennan, C., Hambardzumyan, D., Wee, B., Pena, J., Rouhanifard, S.H., Sohn-Lee, C., le Sage, C., Agami, R., Tuschl, T., and Holland, E.C. “The PTEN-regulating microRNA miR-26a is amplified in high-grade glioma and facilitates gliomagenesis in vivo”. Genes & Development 2009; 23, 1327-1337.

Becher O.J., Hambardzumyan D., Walker T.R., Helmy K., Nazarian J., Albrecht S., Hiner R.L., Gall S., Huse J.T., Jabado N., MacDonald T.J., Holland E.C. “Preclinical evaluation of radiation and perifosine in a genetically and histologically accurate model of brainstem glioma.”. Cancer Res 2010; 70, 2548-2557.

Ney, D.E., Huse, J.T., Dunkel, I.J., Steinherz, P.G., Haque, S., Khakoo, Y. “Intraventricular Meningioma After Cranial Irradiation for Childhood Leukemia”. J of Child Neurol 2010; 25, 1292-1295.

Ozawa, T., Brennan, C.W., Wang, L., Squatrito, M., Sasayama, T., Nakada, M., Huse, J.T., Pedraza, A., Utsuki, S., Yasui, Y., Tandon, A., Fomchenko, E.I., Oko, H., Levine, R.L., Fujii, K., Ladanyi, M., Holland, E.C. “PDGFRA gene rearrangements are frequent genetic events in PDGFRA-amplified glioblastomas.” Genes & Development 2010; 24, 2205-2218.

Squatrito, M. Brennan, C.W., Helmy, K., Huse, J.T., Petrini, J.H., Holland, E.C. “Loss of ATM/Chk2/p53 pathway components accelerates tumor development and contributes to radiation resistance in gliomas”. Cancer Cell 2010; 18, 619-629.

Fomchenko, E.I., Dougherty, J.D., Helmy, K.Y., Katz, A.M., Pietras, A., Brennan, C.W., Huse, J.T., Milosevic, A., Holland, E.C. “Recruited cells can become transformed and overtake PDGF-induced murine gliomas in vivo during tumor progression”. PLoS One 2011; 6, e20605.

Palaskas, N., Larson, S.M., Schultz, N., Komisopoulou, E., Wong, J., Rohle, D., Campos, C., Yannuzzi, N. Osbourne, J.R., Linkov, I., Kastenhuber, E.R., Taschereau, R., Plaiser, S.B., Tran, C., Heguy, A., Wu, H., Sander, C., Phelps, M.E., Brennan, C.W., Port, E., Huse J.T., Graeber, T.G., Mellinghoff, I.K. “18F-fluorodeoxy-glucose positron emission tomography marks MYC-overexpressing human basal-like breast cancers”. Cancer Res 2011; 71, 5164-5174.

Huse, J.T., Nafa, K., Shulka, N., Kastenhuber, E.R., Lavi, E., Hedvat, C.V., Ladanyi, M., Rosenblum, M.K. “High frequency of IDH-1 mutation links glioneuronal tumors with neuropil-like islands to diffuse astrocytomas”. Acta Neuropathol 2011; 122, 367-369.

Litkowski, P.,  Khakoo, Y., Gilheeney, S.W., Souweidane, M., Huse, J.T.,  Haque, S., Young, R.J. “Hemangioma of the cavernous sinus in a child”. Neurology. 2011 Oct 25;77(17):1647-8.

Pulvirenti, T., Van Der Heijden. M., Droms, L.A., Huse, J.T., Tabar, V., Hall, A. “Dishevelled 2 signaling promotes self-renewal and tumorigenicity in human gliomas”.Cancer Res. 2011 Dec 1;71(23):7280-90. Epub 2011 Oct 11.

Morris, L.G.T., Taylor, B.S., Bivona, T.G., Gong, Y., Eng, S., Brennan, C.W., Kaufman, A., Kastenhuber, E.R., Banuchi, V.E., Singh, B., Heguy, A., Viale, A., Mellinghoff, I.K., Huse, J.T., Ganly, I., Chan, T.A. “Genomic dissection of the EGFR/PI3K pathway reveals frequent deletion of the EGFR phosphatase PTPRS in head and neck cancers”. Proc Natl Acad Sci U S A. 2011 Nov 22;108(47):19024-9. Epub 2011 Nov 7.

Gorovets, D., Kannan, K., Kastenhuber, E.R., Islamdoust, N., Campos, C., Pentsova, E., Jhanwar, S.C., Heguy, A., Mellinghoff, I.K., Chan, T.A., Huse, J.T. “IDH mutation and Neuroglial Developmental Features Define Clinically Distinct Subclasses of Lower-Grade Diffuse Astrocytic Glioma”. Clin Cancer Res. 2012 May 1;18(9):2490-501. Epub 2012 Mar 13.

Silber, J., Jacobsen, A., Ozawa, T., Harinath, G., Pedraza, A., Holland, E.C., Sander, C., Huse, J.T. “miR-34a repression in proneural malignant gliomas upregulates expression of its target PDGFRA and promotes tumorigenesis”. PLoS One. 2012;7(3):e33844. Epub 2012 Mar 27.

Reviews and Book Chapters

Huse, J.T. and Doms R.W. “Closing in on the Amyloid Cascade: Recent Insights into the Cell Biology of Alzheimer's Disease”. Mol Neurobiol 2000;22:81-98.

Huse, J.T. and Doms R.W. “Neurotoxic Traffic: Uncovering the Mechanics of Amyloid Production in Alzheimer’s Disease”. Traffic 2001;2:75-81.

Huse, J.T. “Book Review: Neuropathology (Series title: Foundations in Diagnostic Pathology), Editor: Richard Prayson”. Human Pathol 2006;37:244-245.

Huse, J.T. and Holland, E.C. “Genetically Engineered Mouse Models of Brain Cancer and the Promise of Preclinical Testing”. Brain Pathology 2009; 19, 132-143.

Bleau, A.-M., Huse, J.T., Holland, E.C. “The Glioblastoma Resistance Network”. Cell Cycle 2009; 8, 2936-2944.

Huse, J.T. and Holland, E.C. “Yin and yang: cancer-implicated miRNAs that have it both ways”. Cell Cycle 2009; 8, 3611-3612.

Huse, J.T. and Holland, E.C. “Targeting Brain Cancer: Advances in the Molecular Pathology of Malignant Glioma and Medulloblastoma”. Nature Rev Cancer 2010; 10, 319-331.

Huse, J.T., Phillips, H., and Brennan, C.W. “Molecular Subclassification of Diffuse Gliomas: Seeing Order in the Chaos”. Glia 2011; 58, 1190-1199.