Nowak U, Matthews A, Zheng S and Chaudhuri J. The splicing regulator PTBP2 is an AID interacting protein and promotes binding of AID to switch region DNA. Nat Immunol. 2011 Feb;12(2):160-6. Epub 2010 Dec 26.
Lee-Theilen M, Matthews AJ, Kelly D, Zheng S and Chaudhuri J. CtIP promotes microhomology-mediated end-joining during class switch recombination. Nat Struct Mol Biol. 2011 Jan;18(1):75-9. Epub 2010 Dec 5.
Lee-Theilen M and Chaudhuri J. (2010) Walking the AID tightrope. Nat Immunol. 11: 107-109.
Vuong BQ, Lee M, Kabir S, Irima C, Macciarulo G, McKnight GS and Chaudhuri J. (2009) Specific recruitment of PKA to the immunoglobulin locus regulates class switch recombination. Nature Immunology, 10:420-426.
Cheng HL+, Vuong BQ+, Basu UB+, Franklin F, Schwer B, Astarira J, Phan RT, Datta A, Manis J, Alt FW and Chaudhuri J. (2009) Integrity of the AID serine-38 phosphorylation site is critical for class switch recombination and somatic hypermutation in mice. Proc. Natl. Acad. Sci. 106:2717-2722. (+equal contribution)
Chaudhuri J, Basu U, Zrrin A, Yan C, Franco S, Perlot T, Vuong B, Wang J, Phan RT, Datta A, Manis J and Alt FW. (2007). Evolution of immunoglobulin heavy chain class switch recombination mechanism. Advances in Immunology, 94:157-214.
Basu U+, Chaudhuri J+,, Alpert C, Dutt S, Ranganath S, Li G, Schrum JP, Manis JP, Alt FW. (2005) The AID antibody diversification enzyme is regulated by protein kinase A phosphorylation. Nature. 438(7067):508-11. (+ equal contributions)
Chaudhuri J, Khuong C, and Alt FW. (2004) Replication Protein A interacts with AID to promote deamination of somatic hypermutation targets. Nature, 430: 992-998.
Chaudhuri J, Tian M, Khuong C, Pinaud E, Alt FW. (2003) Transcription-targeted DNA deamination by the AID antibody diversification enzyme. Nature, 422:726-730.
Chaudhuri J and Alt FW. (2004) Class Switch Recombination: Interplay of transcription, DNA deamination and DNA repair. Nature Reviews Immunology. 4: 541-52
Zarrin AA, Alt FW, Chaudhuri J, Stokes N, Kaushal D, Du Pasquier L and Tian M. (2005) An evolutionarily conserved target motif for immunoglobulin class-switch recombination. Nat Immunol, 5:1275-1281.
Dudley DD, Chaudhuri J, Bassing CH, Alt FW (2005) Mechanism and Control of V(D)J Recombination versus Class Switch Recombination: Similarities and Differences. Adv Immunol, 86: 43-112.
Rooney S, Chaudhuri J, and Alt FW. (2004) The role of the non-homologous end-joining pathway in lymphocyte development. Immunological Reviews. 200: 115-131.
Dedeoglu F, Horwitz B, Chaudhuri J, Alt FW, Geha RS. (2004) Induction of AID gene expression by IL-4 and CD40 ligation is dependent on STAT6 and NFkB. Int. Immunol. 16: 395-404.
Gao Y, Chaudhuri J, Zhu C, Davidson L, Weaver DT, Alt FW. (1998) A targeted DNA-PKcs-null mutation reveals DNA-PK-independent functions for KU in V(D)J recombination. Immunity. 9:367-76.
medicine (MEH-dih-sin)
Refers to the practices and procedures used for the prevention, treatment, or relief of symptoms of a diseases or abnormal conditions. This term may also refer to a legal drug used for the same purpose.
Source: The National Cancer Institute's Dictionary of Cancer Terms
(http://www.cancer.gov/dictionary)National Institutes of Health (NA-shuh-nul IN-stih-TOOTS … helth)
A federal agency in the U.S. that conducts biomedical research in its own laboratories; supports the research of non-Federal scientists in universities, medical schools, hospitals, and research institutions throughout the country and abroad; helps in the training of research investigators; and fosters communication of medical information. Access the National Institutes of Health Web site at . Also called NIH.
Source: The National Cancer Institute's Dictionary of Cancer Terms
(http://www.cancer.gov/dictionary)
