Office phone:
212-639-6712 Laboratory phone:
212-639-6713 Laboratory fax:
212-717-3135 E-mail:
jonathan@ximpact4.ski.mskcc.org Affiliation:
Structural Biology Program Research topics:
Protein Folding & Trafficking; Structural Biology Research in the Goldberg laboratory is focused on a molecular description of the mechanisms of vesicle transport and compartmentation in eukaryotic cells. We use x-ray crystallography to determine protein atomic structures and biochemical analyses to elucidate mechanisms. Current studies encompass three areas:
- Mechanisms for cargo packaging into transport vesicles
- Architecture of vesicle coats
- Vesicle trafficking processes in disease
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