Liang Deng: Selected Publications

Cao H, Dai P, Wang W, Li H, Yuan J, Wang F, Fang CM, Pitha PM, Liu J, Condit RC, McFadden G, Merghoub T, Houghton AN, Young JW, Shuman S, Deng L. Innate immune response of human plasmacytoid dendritic cells to poxvirus infection is subverted by vaccinia E3 via its Z-DNA/RNA binding domain. PLoS One. 2012;7(5):e36823. Epub 2012 May 14.

Dai, P., H. Cao, T. Merghoub, F. Avogadri, W. Wang, T. Parikh, C. M. Fang, P. M. Pitha, K. Fitzgerald, M. M. Rahman, G. McFadden, X. Hu, A. N. Houghton, S. Shuman, and L. Deng. (2011). Myxoma virus induces type I interferon production in murine plasmacytoid dendritic cells via a TLR9/MyD88-, IRF5/IRF7-, and IFNAR-dependent pathway. J Virol 85:10814-10825.

Deng, L., P. Dai, T. Parikh, H. Cao, V. Bhoj, Q. Sun, Z. Chen, T. Merghoub, A. Houghton, and S. Shuman. (2008). Vaccinia virus subverts a mitochondrial antiviral signaling protein-dependent innate immune response in keratinocytes through its double-stranded RNA binding protein, E3. J Virol 82:10735-10746.

Deng, L., P. Dai, A. Ciro, D. F. Smee, H. Djaballah, and S. Shuman. (2007). Identification of novel antipoxviral agents: mitoxantrone inhibits vaccinia virus replication by blocking virion assembly. J Virol 81:13392-13402.

Deng, L., P. Dai, W. Ding, R. D. Granstein, and S. Shuman. (2006). Vaccinia virus infection attenuates innate immune responses and antigen presentation by epidermal dendritic cells. J Virol 80:9977-9987.

Deng, L., W. Ding, and R. D. Granstein. (2003). Thalidomide inhibits tumor necrosis factor-alpha production and antigen presentation by Langerhans cells. J Invest Dermatol 121:1060-1065.

Ding, W., S. Beissert, L. Deng, E. Miranda, C. Cassetty, K. Seiffert, K. L. Campton, Z. Yan, G. F. Murphy, J. A. Bluestone, and R. D. Granstein. (2003). Altered cutaneous immune parameters in transgenic mice overexpressing viral IL-10 in the epidermis. J Clin Invest 111:1923-1931.

Deng, L., and S. Shuman. (1998). Vaccinia NPH-I, a DExH-box ATPase, is the energy coupling factor for mRNA transcription termination. Genes Dev 12:538-546.

Deng, L., J. Hagler, and S. Shuman. (1996). Factor-dependent release of nascent RNA by ternary complexes of vaccinia RNA polymerase. J Biol Chem 271:19556-19562.

Deng, L., and S. Shuman. (1994). A role for the H4 subunit of vaccinia RNA polymerase in transcription initiation at a viral early promoter. J Biol Chem 269:14323-14328.

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