Jennifer Tsai, MD

Research Fellow
Lab Phone:
University of Otago, New Zealand

Medical management for radiation casualties has been difficult owing to the complexity of radiation-induced pathophysiology. Casualties can present with a wide range of symptoms involving neurovascular, gastrointestinal, and hematological systems, but a significant number of morbidities and mortalities is attributable to immunosuppression since the hematopoietic cells are most susceptible to radiation injury. There is an acute decline in circulating lymphoid cell counts within mere hours after radiation exposure; in contrast, granulocyte and erythrocyte counts decrease over the course of days and weeks. In anticipation of potential radiation mass casualty exposures, our lab aims to develop strategies to specifically enhance lymphoid recovery in such circumstances.