Michelle S. Bradbury: Publications

Suteewong T, Sai H, Hovden R, Muller D, Bradbury M, Gruner S, Wiesner U. Multicompartment Mesoporous Silica Nanoparticles with Branched Shapes: An Epitaxial Growth Mechanism (under revision, Science).

Phillips E, Penate-Medina O, Zanzonico PB, Ow H, Carvajal RD, Mohan P, Ye Y, Humm J, Kaliagian H, Schöder H, Strauss W, Larson SM, Wiesner U, & Bradbury MS. Clinical Translation of an Ultrasmall Optical Hybrid Nanoparticle Probe (submitted, Angewandte Chemie).

Suteewong T, Sai, H, Bradbury MS, Estroff L, Gruner S, Wiesner U. Synthesis and Formation Mechanism of Aminated Mesoporous Silica Nanoparticles. Chem Mater 24: 3895-3905, 2012.

Benezra M, Hambardzumyan D, Penate-Medina O, Pillarsetty K, Veach D, Smith-Jones P, Zanzonico P, Phillips E, Ozawa T, Longo V, Holland E, Larson S, and Bradbury M. Fluorine-labeled Dasatinib Nanoformulations as Novel Targeted Molecular Imaging Probes in PDGFR-expressing Transgenic High Grade Glioma Models. Neoplasia 14:1132-1143, 2012.

Benezra M*, Penate-Medina O*, Zanzonico P, Schaer D, Ow H, Burns A, De Stanchina E, Longo V, Herz E, Iyer S, Wolchok J, Larson S, Wiesner U, Bradbury MS. Multimodal silica nanoparticles are effective cancer targeted probes in a model of human melanoma. J Clin Invest 121:2768-2780, 2011. (*co-first authors)

Zinn KR, Anderson CJ, Bradbury M, Cutler CS, Peterson TE, Morgan DE, Price JC, Graham MM, Wittstrom K, Norenberg JP. Components of a curriculum for molecular imaging scientists. J. Nucl Med 52:650-656, 2011. 

Penate Medina O, Haikola M, Tahtinen M, Simpura I, Kaukinen S, Valtanen H, Zhu Y, Wei C, Reunanen J, Nurminen T, Smith-Jones P, Bradbury M, Larson S, Kairemo K. Liposomal tumor targeting in drug delivery and imaging using MMP-2 and MMP-9 binding ligands. J Drug Delivery 2011:1-9, 2011. 

Pitter KL, Galbán CJ, Galbán S, Saeed-Tehrani O, Li F, Charles N, Bradbury MS, Becher OJ, Chenevert TJ, Rehemtulla A, Ross B, Holland E, Hambardzumyan D. Perifosine and CCI 779 co-operate to induce cell death and cell cycle arrest in PTEN-intact and PTEN-deficient PDGF-driven mouse high-grade glioma. PLoS ONE 6:e14545, 2011. 

Suteewong T, Sai H, Cohen R, Wang S, Bradbury M, Baird B, Gruner S, and Wiesner, U. Highly aminated mesoporous silica nanoparticles with cubic pore structure. J Am Chem Soc 133:172-175, 2011. 

Suteewong T, Sai H, Lee J, Bradbury M, Hyeon T, Gruner S, Wiesner U. Ordered mesoporous silica nanoparticles with and without embedded iron oxide nanoparticles: structure evolution during synthesis. J Mater Chem 20:7807-7814, 2010.

Burns A, Vider J, Ow H, Herz E, Penate-Medina O, Baumgart M, Larson S, Wiesner U, Bradbury MS. Fluorescent silica nanoparticles with efficient urinary excretion for nanomedicine. Nano Letters, 9: 442-448, 2009. 

Peck KK, Bradbury MS, Psaty EL, Petrovich N, Holodny AI. Joint activation of SMA and pre-SMA during simultaneous motor and language fMRI. NeuroReport 20:487-491, 2009. 

Peck K, Bradbury MS, Hou B, Petrovich N, Holodny A. The role of the supplementary motor area (SMA) in the execution of primary motor activities in brain tumor patients: functional MRI detection of time-resolved differences in the hemodynamic response. Med Sci Monit 15:MT55-62, 2009. 

Peck KK, Bradbury MS, Petrovich N, Hou BL, Ishill N, Brennan C, Tabar V, Holodny AI.  Presurgical evaluation of language using functional magnetic resonance imaging in brain tumor patients with previous surgery. Neurosurgery 64:652-3, 2009.

Bradbury MS, Hambardzumyan D, Zanzonico P, Schwartz J, Cai S, Burnazi E, Larson  SM, Holland EC. Dynamic small-animal PET imaging of tumor proliferation with 3′-deoxy-3′-18F fluorothymidine in a genetically engineered mouse model of high-grade gliomas. J Nucl Med 49:422-429, 2008. 

Panagiotakos G, Al Shamy G, Chan B, Abrams R, Greenberg E, Saxena A, Bradbury MS, Gutin P, Tabar V. Long-term impact of radiation on the stem cell and oligodendrocyte precursors in the brain. PLoS One 2:e588, 2007. 

Bradbury MS, Panagiotakos G, Tomishima M, Zanzonico P, Vider J, Ponomarev V, Chan B, Studer L, Tabar V. Optical bioluminescence imaging of human ES cell progeny in the rodent CNS. J Neurochem 102:2029-2039, 2007. 

Barberi T, Bradbury MS, Dinzer Z, Panagiotakos G, Socci N, Studer L. Derivation of engraftable skeletal myoblasts from human embryonic stem cells. Nat Med 13:642-648, 2007. 

Hou BL, Bradbury MS, Peck KK, Petrovich NM, Gutin PL, Holodny AI. Effect of brain tumor neovasculature defined by rCBV on BOLD fMRI activation volume in the primary motor cortex. Neuroimage 32:489-497, 2006.

Adler LP, Weinberg IN, Bradbury MS, Levine E, Lesko NM, Geisinger K, Berg W, Freimanis R. Method of combined FDG-PET and radiographic imaging of primary breast cancers. The Breast J 9:163-166, 2003.

Manuscripts, Revision Manuscript Submitted

Benezra M, Phillips E, Butler J, Dobrenkov K, Siim B, Chaplin D, Rafii S, Rabbany S, Bradbury M. Monitoring of human systemic and xenograft models of leukemia using a novel vascular disrupting agent. 

Benezra M, Hambardzumyan D, Penate-Medina O, Pillarsetty K, Veach D, Smith-Jones P, Zanzonico P, Phillips E, Ozawa T, Longo V, Holland E, Larson S, Bradbury M. Fluorine-labeled dasatinib nanoformulations as novel targeted molecular imaging probes in PDGFR-expressing transgenic high-grade glioma models.

Suteewong T, Sai H, Bradbury M, Gruner S, Wiesner U. Synthesis and formation mechanism of aminated mesoporous silica nanoparticles.

Books, Book Chapters, and Reviews

Envisioning the future of molecular neuroimaging and translational nanomolecular probes. In: Bradbury M, Meade T, and Hammoud D, eds. Molecular Imaging, Special Edition. Philadelphia: Decker, Inc., 2012 (in progress).

Bradbury MS. The role of molecular imaging in personalized medicine. In: Faro S and Mohamed FB, eds. Functional Neuroradiology: Principles and Clinical Applications. New York: Springer, 2011.

Zapadka ME, Bradbury MS, Williams DW.  The brain and its coverings. In: Chen MYM, Pope TL, and Ott DJ, eds. Basic Radiology, 2nd ed. New York: McGraw-Hill, 2010.

Bradbury MS, Hricak HH, Heath JR. Systems biology and nanotechnology: linking cancer biology and imaging. In: Reiser MF, Semmler W, and Hricak H, eds. Magnetic Resonance Tomography. Berlin and Heidelberg: Springer-Verlag (November 2007).

Bradbury MS, Gutin PH. The potential of ferumoxytol nanoparticle magnetic resonance imaging, perfusion, and angiography in central nervous system malignancy: A pilot study [Letter]. Neurosurgery 60(4):601-612, 2007.

Bradbury MS, Hricak HH. Molecular magnetic resonance imaging in oncology: future directions. In: Martin DR, ed. MR Imaging Clinics of North America. Philadelphia: W.B. Saunders Co, 2005.

Bradbury MS, Gutin PH. Associations among magnetic resonance spectroscopy, apparent diffusion coefficients, and image-guided histopathology [Letter]. Neurosurgery 54(5):1118-1119, 2004.

Hricak HH, Akin O, Bradbury MS, Liberman L, Schwartz L, Larson S. Advanced imaging methods. In: DeVita VT, Hellman S, and Rosenberg SA, eds. Cancer: Principles and Practice of Oncology, 7th ed. Philadelphia: Lippincott Williams & Wilkins, 2004.

Chen MY, Bradbury MS.  Scope of diagnostic imaging. In: Chen MYM, Pope TL, and Ott DJ, eds.  Basic Radiology. New York: McGraw-Hill, 2004.

Bradbury MS, Kavanagh PV, Chen MY, Weber TM, Bechtold RE.  Non-invasive assessment of portomesenteric venous thrombosis: current concepts and imaging strategies. J Comput Assist Tomogr 26: 392-404, 2002.

Bradbury MS, Kavanagh PV, Bechtold RE, Chen MY, Ott DJ, Weber TM. Mesenteric venous thrombosis: diagnosis and noninvasive imaging. Radiographics 22: 527-541, 2002.