Richard J. O'Reilly: Publications

Koehne G, Gallardo H, Sadelain M, O'Reilly RJ. Rapid selection of antigen-specific T-lymphocytes by retroviral transduction. Blood, 96:109-117, 2000.

Koehne G, Smith KM, Dupont B, O'Reilly RJ. Quantitation, selection and functional characterization of EBV-specific and alloreactive T cells detected by intracellular interferon-g production and growth of cytotoxic precursors. Blood, 99:1730-1740, 2002.

Doubrovina ES, Doubrovin MM, Bider E, Sisson RB, O'Reilly RJ, Dupont B, Vyas YM. Evasion from natural killer cell immunity by MIC expressing colon adenocarcinoma. J Immunology. 171:6891-6899, 2003.

Dupont J, Wang X, Marshall D, Leitao M, Hedvat C, Hummer A, Thaler H, O'Reilly R, Soslow R, Wilms tumor gene (WT1) and p53 expression in ovarian and endometrial carcinomas: a study of 130 cases using tissue microarrays. Gynecol Oncol. Aug;94(2):449-55, 2004.

Doubrovina ES, Doubrovin MM, Lee S, Shieh JH, Heller G, Pamer E, O'Reilly RJ. In vitro stimulation with WT1 peptide-loaded Epstein-Barr virus-positive B cells elicits high frequencies of WT1 peptide -specific T cells with in vitro tumoricidal activity. Clinical Cancer Research. Nov 1;10(21):7207-7219, 2004.

Trivedi D, Williams RY, O'Reilly RJ, Koehne G. Generation of cytomegalovirus (CMV)-specific T-lymphocytes using protein-spanning pools of pp65-derived overlapping pentadecapeptides for adoptive immunotherapy. Blood. April 1 105 (7): 2793-2801, 2005.

Hsu K, Keever-Taylor C, Wilton A, Pinto C, Heller G, Arkun K, O'Reilly R, Horowitz M, Dupont B. Improved outcome in HLA-identical sibling hematopoietic stem-cell transplantation for acute myelogenous leukemia by KIR and HLA genotypes. Blood.Jun 15;105(12):4878-84, 2005.

Zanzonico P, Koehne G, Gallardo H, Doubrovin M, Doubrovina E, Finn R, Blasberg R, O'Reilly R, Sadelain M, Larson S. [131I]-FIAU Labeling of Genetically transduced, tumor-reactive lymphocytes: cell-level dosimetry and dose-dependent toxicity. European Journal of Nuclear Medicine and Molecular Imaging. Sep;33(9):988-97, 2006.

Doubrovin MM, Doubrovina ES, Zanzonico P, Sadelain M, Larson SM, O'Reilly RJ. In vivo imaging and quantitation of adoptively transported human antigen-specific T-cells transduced to express a human nor-epinephrine transporter gene. Cancer Research. 2007 Dec 15;67(24):11959-69.

Almyroudis NG, Jakubowski A, Jaffe D, Sepkowitz K, Pamer E, O'Reilly RJ, Papanicolaou GA. Predictors for persistent cytomegalovirus reactivation after T-cell-depleted allogeneic hematopoietic stem cell transplantation. Transplant Infectious Disease. 2007 Dec;9(4):286-94. Epub 2007 May 19.

Hasan AN, Selvakumar A, Doubrovina E, Riviere I, Sadelain MW, O'Reilly RJ. Artificial antigen presenting cells that express prevalent HLA alleles: A step towards the broad application of antigen-specific adoptive cell therapies. Discov Med. 2009 Dec;8(43):210-8. Review.

Hasan AN, Kollen WJ, Trivedi D, Selvakumar A, Dupont B, Sadelain M, O'Reilly RJ. A panel of artificial APCs expressing prevalent HLA alleles permits generation of cytotoxic T cells specific for both dominant and subdominant viral epitopes for adoptive therapy. J Immunol. 2009 Aug 15;183(4):2837-50. Epub 2009 Jul 27.

O'Reilly RJ, Doubrovina E, Trivedi D, Hasan A, Kollen W, Koehne G. Adoptivetransfer of antigen-specific T-cells of donor type for immunotherapy of viral infections following allogeneic hematopoietic cell transplants. Immunol Res. 2007;38(1-3):237-50.