Our laboratory currently has openings for postdoctoral fellows and a research technician.
We are recruiting to fill a postdoctoral position. The laboratory has a broad interest in the mechanisms underlying genomic evolution during cancer progression and metastasis. We utilize genetic and small molecule screening approaches in the zebrafish, a model organism which allows for characterization of tumor and host cells during each phase of tumor evolution.
Applicants should be interesting in utilizing techniques commonly applied to evolutionary biology in the setting of cancer. The relevance of this approach can be appreciated when considering the thousands of mutations found in a typical tumor, and we are interested in understanding the mechanistic basis of variant generation and selection pressures in the rapidly changing tumor microenvironment. We are particularly interested in understanding how the host genetic background interacts with DNA/RNA variants in the tumor cell itself. Our techniques include high throughput whole genome, RNA-seq and ChIP-seq, along with chemical biology techniques.
The position will offer the opportunity for extensive scientific collaborations across diverse disciplines in a highly stimulating, creative environment. Applicants with a background in evolutionary genomics/biology, computational biology or cancer biology are encouraged to apply.