Sotillo, R., Hernando, E., Diaz-Rodriguez, E., Teruya-Feldstein, J., Cordon-Cardo, C., Lowe, S.W. and Benezra, R. (2007). Mad2 overexpression promotes aneuploidy and tumorigenesis in mice. Cancer Cell 11:9-23.
Jankovic, V., Ciarrocchi, A., Boccuni, P., Deblasio, T., Benezra, R. and Nimer, S (2007) Id1 restrains myeloid commitment, maintaining the self-renewal capacity of hematopoietic stem cells. PNAS 104: 1260-1265.
Gupta, G.P., Perk, J., Swarnali, A., de Candia, P., Mittal, V., Todorova-Manova, K., Greald, W.L., Brogi, E., Benezra, R*., and Massague, J*. (2007) Id genes mediate tumor re-initiation during breast cancer lung metastasis. Proc Natl Acad Sci USA 104:19506-11. Co-corresponding authors.
Ciarrocchi, A., Jankovic, V., Shaked, Y., Nolan, D., Mittal, V., Kerbel, R., Nimer, S. and Benezra, R. (2007) Id1 restrains p21 expression to control endothelial progenitor cell formation. PloS One 2(12):p. e1338.
Henke, E., Perk, J., Vider, P., DeCandia, P., Chin, Y., Solit,D.B., Ponomarev, L., Cartegni, K., Manova, N., Rosen, N. and Benezra, R. (2008) Peptide conjugated antisense oligonucleotides for targeted inhibition of transcriptional regulator in vivo. Nature Biotechnology 26(1)91-100.
Diaz-Rodriguez, E., Sotillo, R., Schvartzman, JM., and Benezra, R. (2008) Hec1 overexpression hyperactivates the mitotic checkpoint and induces tumor formation in vivo. Proc Natl Acad Sci USA 105:16719-16724.
Nam, H-s. and Benezra, R. (2009) High levels of Id1 expression define B1 type adult neural stem cells. Cell Stem Cell 5, 515-526.
Schvartzman, J-M*, Sotillo, R.*, and Benezra, R. (2009) Mitotic chromosomal instability and cancer: Mouse modeling of the human disease. Nat Rev Cancer, 10(2): 102-115 * Both authors contributed equally.
Sotillo, R., Schvartzman, J-M., Socci, N.D. and Benezra, R. (2009) Mad2-induced chromosome instability leads to lung tumor relapse after oncogene withdrawal. Nature, 64(7287): 436-440.
Schvartzman, JM., Duijf, P., Sotillo, R., Coker, C., & Benezra, R. (2011). Mad2 is a critical mediator of chromosome instability observed upon Rb and p53 pathway inhibition. Cancer Cell. 19(6):701-14.
Granot, Z., Henke, E., Comen, E., King, T., Norton, L. & Benezra, R. (2011). Tumor entrained neutrophils inhibit seeding in the pre-metastatic lung. Cancer Cell. 20(3):300-1.
Ono, Y., Masuda, S., Nam, H-s., Benezra, R., Miyagoe-Suzuki, Y. and Takeda, S. (2011). Slow-dividing satellite cells retain long-term self-renewal ability in adult muscle. J of Cell Science.
Barrett, L.E., Granot, Z., Coker, C., Iavarone, A., Hambardzumyan, D., Holland, E., Nam, H-s., & Benezra, R., (2012).Self-renewal does not predict tumor growth potential in mouse model of high-grade glioma. Cancer Cell. 21(1) 11-24.
Romero, E., Pavlovic, S., Amlani, B., Chin, Y. and Benezra, R.(2011) Id1 maintains embryonic stem cell self-renewal by up-regulation of Nanog and repression of Brachyury expression. Stem Cell and Dev.,21(3):384-93. ;
cell (sel)
The individual unit that makes up the tissues of the body. All living things are made up of one or more cells.
Source: The National Cancer Institute's Dictionary of Cancer Terms
(http://www.cancer.gov/dictionary)medicine (MEH-dih-sin)
Refers to the practices and procedures used for the prevention, treatment, or relief of symptoms of a diseases or abnormal conditions. This term may also refer to a legal drug used for the same purpose.
Source: The National Cancer Institute's Dictionary of Cancer Terms
(http://www.cancer.gov/dictionary)National Institutes of Health (NA-shuh-nul IN-stih-TOOTS … helth)
A federal agency in the U.S. that conducts biomedical research in its own laboratories; supports the research of non-Federal scientists in universities, medical schools, hospitals, and research institutions throughout the country and abroad; helps in the training of research investigators; and fosters communication of medical information. Access the National Institutes of Health Web site at . Also called NIH.
Source: The National Cancer Institute's Dictionary of Cancer Terms
(http://www.cancer.gov/dictionary)
