Urs Stephen Rutishauser: Publications

El Maarouf A, Moyo-Lee Yaw and Rutishauser U. 2014 Improved Stem Cell-Derived Motoneuron Survival, Migration, Sprouting and Innervation with Enhanced Expression of Polysialic Acid. Cell Transplantation 2014, Mar 3.

Battista D, Ganat Y, El Maarouf A, Studer L and Rutishauser U. 2014 Enhancement of polysialic acid expression improves function of ES-derived dopamine neuron grafts in Parkinsonian mice. Stem Cells Translational Medicine 2014; 3(1): 108-113.

Mousumi Ghosh, Luis M. Tuesta, Rocio Puentes, Samik Patel, Kiara Melendez, Abderrahman El Maarouf, Urs Rutishauser, Damien D. Pearse.  2012 PST-expressing Schwann cells readily migrate, support corticospinal axon regeneration and promote functional restitution after implantation into the contused spinal cord , Glia. 2012; 60(6):979-92.

Yosif M. Ganat, Sonja Kriks, Elizabeth L. Calder, Edmund Y. Tu , Fan Jia, Neil Harrison, Mark J. Tomishima, Urs Rutishauser and Lorenz Studer. 2012  BAC transgenic ESC reporter line analysis identifies midbrain dopaminergic neuron stages suitable for efficient in vivo engraftment and in vitro gene discovery J Clin Invest. Aug 1;122(8):2928-39. Epub 2012 Jul.

Battista D, Rutishauser U.  (2010) Removal of polysialic acid triggers dispersion of subventricularly derived neuroblasts into surrounding CNS tissues.  J Neurosci.  30(11):3995-4003.

Rutishauser, U. (2008) Polysialic acid in the plasticity of the developing and adult vertebrate nervous system. Nat Rev Neurosci. 9(1), 26-35.

Maarouf AE, Rutishauser U. (2010) Use of PSA-NCAM in repair of the central nervous system. Adv Exp Med Biol. 663:137-47.

Franz C.K., Rutishauser, U., Rafuse V.F.  (2008) Intrinsic neuronal properties control selective targeting of regenerating motoneurons.  Brain. Mar 11.


Franz, C.K, Rutishauser, U and Rafuse, V.F. Polysialylated Neural Cell Adhesion Molecule (PSA-NCAM) is necessary for selective targeting of regenerating motor neurons. J. Neuroscience 25: 2081-2091(2005).


Johnson, C.P., Fujimoto, I., Rutishauser, U., and Leckband, D.E. Direct evidence that NCAM polysialylation increases intermembrane repulsion and abrogates adhesion. J. Biol. Chem. 280:137-145 (2005).

Piccoli G., Rutishauser, U., and Bruses, J.L. N-cadherin juxtamembrane domain modulates voltage-gated Ca2+ current via RhoA GTPase and Rho-associated kinase. J. Neurosci. 24:10918-23 (2004).

Petridis, A. K., El Maarouf, A. and Rutishauser, U. Polysialic acid regulates cell contact-dependent neuronal differentiation of progenitor cells from the subventricular zone. Dev. Dynamics 230, 675-684 (2004).

Tricaud, N., Perrin-Tricaud, C., Brusés, J.L. and Rutishauser, U. Adherens junctions in myelinating Schwann cells stabilize Schmidt-Lanterman incisures via recruitment of p120 catenin to E-cadherin. J. Neuroscience, 25, 2081-91 (2005).

El Maarouf, A., Kolesnikov, Y., Pasternak, G. and Rutishauser, U. Polysialic acid-induced plasticity reduces neuropathic insult to the central nervous system. Proc. Natl. Acad. Sci. 102: 11516-20 (2005).

Canger, A.K. and Rutishauser, U. Alteration of neural tissue structure by mexpression of polysialic acid induced by viral delivery of PST polysialyltransferase. Glycobiology 14, 83-93 (2004).

Prosser, R.A., Rutishauser, U. and Glass, J.D. Enzymatic removal of polysialic acid from the SCN blocks optic chiasm-stimulated phase resetting in vitro. J. Neurosci. 23, 652-8 (2003).

Johnson, C.P., Fujimoto, I., Perrin-Tricaud, C., Rutishauser, U., and Leckband, D. Mechanism of homophilic adhesion by the neural cell adhesion molecule: use of multiple domains and flexibility. Proc. Natl. Acad. Sci. 101:6963-8 (2004).

El Maarouf, A. and Rutishauser, U. Removal of polysialic acid induces aberrant pathways, synaptic vesicle distribution and terminal arborization of retinotectal axons. J. Comp. Neurol. 460, 203-11. (2003).