Franz, C.K, Rutishauser, U and Rafuse, V.F. Polysialylated Neural Cell Adhesion Molecule (PSA-NCAM) is necessary for selective targeting of regenerating motor neurons. J. Neuroscience 25: 2081-2091(2005).
Johnson, C.P., Fujimoto, I., Rutishauser, U., and Leckband, D.E. Direct evidence that NCAM polysialylation increases intermembrane repulsion and abrogates adhesion. J. Biol. Chem. 280:137-145 (2005).
Piccoli G., Rutishauser, U., and Bruses, J.L. N-cadherin juxtamembrane domain modulates voltage-gated Ca2+ current via RhoA GTPase and Rho-associated kinase. J. Neurosci. 24:10918-23 (2004).
Petridis, A. K., El Maarouf, A. and Rutishauser, U. Polysialic acid regulates cell contact-dependent neuronal differentiation of progenitor cells from the subventricular zone. Dev. Dynamics 230, 675-684 (2004).
Tricaud, N., Perrin-Tricaud, C., Brusés, J.L. and Rutishauser, U. Adherens junctions in myelinating Schwann cells stabilize Schmidt-Lanterman incisures via recruitment of p120 catenin to E-cadherin. J. Neuroscience, 25, 2081-91 (2005).
El Maarouf, A., Kolesnikov, Y., Pasternak, G. and Rutishauser, U. Polysialic acid-induced plasticity reduces neuropathic insult to the central nervous system. Proc. Natl. Acad. Sci. 102: 11516-20 (2005).
Canger, A.K. and Rutishauser, U. Alteration of neural tissue structure by mexpression of polysialic acid induced by viral delivery of PST polysialyltransferase. Glycobiology 14, 83-93 (2004).
Prosser, R.A., Rutishauser, U. and Glass, J.D. Enzymatic removal of polysialic acid from the SCN blocks optic chiasm-stimulated phase resetting in vitro. J. Neurosci. 23, 652-8 (2003).
Johnson, C.P., Fujimoto, I., Perrin-Tricaud, C., Rutishauser, U., and Leckband, D. Mechanism of homophilic adhesion by the neural cell adhesion molecule: use of multiple domains and flexibility. Proc. Natl. Acad. Sci. 101:6963-8 (2004).
El Maarouf, A. and Rutishauser, U. Removal of polysialic acid induces aberrant pathways, synaptic vesicle distribution and terminal arborization of retinotectal axons. J. Comp. Neurol. 460, 203-11. (2003).
medicine (MEH-dih-sin)
Refers to the practices and procedures used for the prevention, treatment, or relief of symptoms of a diseases or abnormal conditions. This term may also refer to a legal drug used for the same purpose.
Source: The National Cancer Institute's Dictionary of Cancer Terms
(http://www.cancer.gov/dictionary)
National Institutes of Health (NA-shuh-nul IN-stih-TOOTS … helth)
A federal agency in the U.S. that conducts biomedical research in its own laboratories; supports the research of non-Federal scientists in universities, medical schools, hospitals, and research institutions throughout the country and abroad; helps in the training of research investigators; and fosters communication of medical information. Access the National Institutes of Health Web site at . Also called NIH.
Source: The National Cancer Institute's Dictionary of Cancer Terms
(http://www.cancer.gov/dictionary)