Louis V. Gerstner Young Investigator Award, Memorial Sloan-Kettering Cancer Center (2011)
Young Investigator Award, Prostate Cancer Foundation (2011)
Physician Research Training Award, Department of Defense Prostate Cancer Research Program (2010)
Advanced Fellowship Award, Charles H. Revson Foundation (2009)
K08 ClinicalScientist Development Award, National Institutes of Health (2009)
Clinical Scholars Award, Memorial Sloan-Kettering Cancer Center (2008)
Young Investigator Award, American Society of Clinical Oncology (2007)
Clinical Cancer Research Award, American Association for Cancer Research/Bristol-Myers Squibb (2007)
androgen (AN-droh-jen)
A type of hormone that promotes the development and maintenance of male sex characteristics.
Source: The National Cancer Institute's Dictionary of Cancer Terms (http://www.cancer.gov/dictionary)
cancer (KAN-ser)
A term for diseases in which abnormal cells divide without control and can invade nearby tissues. Cancer cells can also spread to other parts of the body through the blood and lymph systems. There are several main types of cancer. Carcinoma is a cancer that begins in the skin or in tissues that line or cover internal organs. Sarcoma is a cancer that begins in bone, cartilage, fat, muscle, blood vessels, or other connective or supportive tissue. Leukemia is a cancer that starts in blood-forming tissue such as the bone marrow, and causes large numbers of abnormal blood cells to be produced and enter the blood. Lymphoma and multiple myeloma are cancers that begin in the cells of the immune system. Central nervous system cancers are cancers that begin in the tissues of the brain and spinal cord. Also called malignancy.
Source: The National Cancer Institute's Dictionary of Cancer Terms (http://www.cancer.gov/dictionary)
cell (sel)
The individual unit that makes up the tissues of the body. All living things are made up of one or more cells.
Source: The National Cancer Institute's Dictionary of Cancer Terms (http://www.cancer.gov/dictionary)
clinical (KLIH-nih-kul)
Having to do with the examination and treatment of patients.
Source: The National Cancer Institute's Dictionary of Cancer Terms (http://www.cancer.gov/dictionary)
differentiation (DIH-feh-REN-shee-AY-shun)
In cancer, refers to how mature (developed) the cancer cells are in a tumor. Differentiated tumor cells resemble normal cells and tend to grow and spread at a slower rate than undifferentiated or poorly differentiated tumor cells, which lack the structure and function of normal cells and grow uncontrollably.
Source: The National Cancer Institute's Dictionary of Cancer Terms (http://www.cancer.gov/dictionary)
drug (drug)
Any substance, other than food, that is used to prevent, diagnose, treat or relieve symptoms of a disease or abnormal condition. Also refers to a substance that alters mood or body function, or that can be habit-forming or addictive, especially a narcotic.
Source: The National Cancer Institute's Dictionary of Cancer Terms (http://www.cancer.gov/dictionary)
endogenous (en-DAH-jeh-nus)
Produced inside an organism or cell. The opposite is external (exogenous) production.
Source: The National Cancer Institute's Dictionary of Cancer Terms (http://www.cancer.gov/dictionary)
ETS
Smoke that comes from the burning of a tobacco product and smoke that is exhaled by smokers. Inhaling ETS is called involuntary or passive smoking. Also called environmental tobacco smoke and secondhand smoke.
Source: The National Cancer Institute's Dictionary of Cancer Terms (http://www.cancer.gov/dictionary)
fusion protein (FYOO-zhun PROH-teen)
A protein made from a fusion gene, which is created by joining parts of two different genes. Fusion genes may occur naturally in the body by transfer of DNA between chromosomes. For example, the BCR-ABL gene found in some types of leukemia is a fusion gene that makes the BCR-ABL fusion protein. Fusion genes and proteins can also be made in the laboratory by combining genes or parts of genes from the same or different organisms.
Source: The National Cancer Institute's Dictionary of Cancer Terms (http://www.cancer.gov/dictionary)
gene (jeen)
The functional and physical unit of heredity passed from parent to offspring. Genes are pieces of DNA, and most genes contain the information for making a specific protein.
Source: The National Cancer Institute's Dictionary of Cancer Terms (http://www.cancer.gov/dictionary)
genetic (jeh-NEH-tik)
Inherited; having to do with information that is passed from parents to offspring through genes in sperm and egg cells.
Source: The National Cancer Institute's Dictionary of Cancer Terms (http://www.cancer.gov/dictionary)
genome (JEE-nome)
The complete genetic material of an organism.
Source: The National Cancer Institute's Dictionary of Cancer Terms (http://www.cancer.gov/dictionary)
investigator (in-VES-tih-gay-ter)
A researcher in a clinical trial or clinical study.
Source: The National Cancer Institute's Dictionary of Cancer Terms (http://www.cancer.gov/dictionary)
medicine (MEH-dih-sin)
Refers to the practices and procedures used for the prevention, treatment, or relief of symptoms of a diseases or abnormal conditions. This term may also refer to a legal drug used for the same purpose.
Source: The National Cancer Institute's Dictionary of Cancer Terms (http://www.cancer.gov/dictionary)
phenotype
The observable characteristics in an individual resulting from the expression of genes; the clinical presentation of an individual with a particular genotype.
Source: The National Cancer Institute's Dictionary of Cancer Terms (http://www.cancer.gov/dictionary)
physician (fih-ZIH-shun)
Medical doctor.
Source: The National Cancer Institute's Dictionary of Cancer Terms (http://www.cancer.gov/dictionary)
prostate (PROS-tayt)
A gland in the male reproductive system. The prostate surrounds the part of the urethra (the tube that empties the bladder) just below the bladder, and produces a fluid that forms part of the semen.
Source: The National Cancer Institute's Dictionary of Cancer Terms (http://www.cancer.gov/dictionary)
prostate cancer (PROS-tayt KAN-ser)
Cancer that forms in tissues of the prostate (a gland in the male reproductive system found below the bladder and in front of the rectum). Prostate cancer usually occurs in older men.
Source: The National Cancer Institute's Dictionary of Cancer Terms (http://www.cancer.gov/dictionary)
PTEN
A protein that helps control many cell functions, including cell division and cell death. Mutations (changes) in the gene that makes PTEN are found in many types of cancer and other diseases. It is a type of tumor suppressor protein. Also called PTEN tyrosine phosphatase.
Source: The National Cancer Institute's Dictionary of Cancer Terms (http://www.cancer.gov/dictionary)
receptor (reh-SEP-ter)
A molecule inside or on the surface of a cell that binds to a specific substance and causes a specific physiologic effect in the cell.
Source: The National Cancer Institute's Dictionary of Cancer Terms (http://www.cancer.gov/dictionary)
response (reh-SPONTS)
In medicine, an improvement related to treatment.
Source: The National Cancer Institute's Dictionary of Cancer Terms (http://www.cancer.gov/dictionary)
scientist (SY-en-tist)
A person who has studied science, especially one who is active in a particular field of investigation.
Source: The National Cancer Institute's Dictionary of Cancer Terms (http://www.cancer.gov/dictionary)
significant (sig-NIH-fih-kunt)
In statistics, describes a mathematical measure of difference between groups. The difference is said to be significant if it is greater than what might be expected to happen by chance alone. Also called statistically significant.
Source: The National Cancer Institute's Dictionary of Cancer Terms (http://www.cancer.gov/dictionary)
tissue (TIH-shoo)
A group or layer of cells that work together to perform a specific function.
Source: The National Cancer Institute's Dictionary of Cancer Terms (http://www.cancer.gov/dictionary)
transcription (tran-SKRIP-shun)
In biology, the process by which a cell makes an RNA copy of a sequence of DNA that is a gene.
Source: The National Cancer Institute's Dictionary of Cancer Terms (http://www.cancer.gov/dictionary)
transformation (TRANZ-for-MAY-shun)
In medicine, the change that a normal cell undergoes as it becomes malignant.
Source: The National Cancer Institute's Dictionary of Cancer Terms (http://www.cancer.gov/dictionary)
translocation (TRANZ-loh-KAY-shun)
A type of chromosomal abnormality in which a chromosome breaks and a portion of it reattaches to a different chromosomal location.
Source: The National Cancer Institute's Dictionary of Cancer Terms (http://www.cancer.gov/dictionary)
tumor (TOO-mer)
An abnormal mass of tissue that results when cells divide more than they should or do not die when they should. Tumors may be benign (not cancer), or malignant (cancer). Also called neoplasm.
Source: The National Cancer Institute's Dictionary of Cancer Terms (http://www.cancer.gov/dictionary)
will (wil)
A legal document in which a person states what is to be done with his or her property after death, who is to carry out the terms of the will, and who is to care for any minor children.
Source: The National Cancer Institute's Dictionary of Cancer Terms (http://www.cancer.gov/dictionary)
Zheng (jung)
In traditional Chinese medicine, a way of diagnosing disease based on observing a set of signs and symptoms. A practitioner checks Zheng by looking at the patient; asking questions; feeling the pulse, organs, and tissues; listening to body sounds; and smelling the body.
Source: The National Cancer Institute's Dictionary of Cancer Terms (http://www.cancer.gov/dictionary)
