Research: New & Noteworthy

Pictured: Pseudomonas aeruginosa
The Enemy’s Telltale Mark: Researchers Find Novel Way Body Defends against Harmful Bacteria

MSK researchers discover that the body senses and attacks harmful bacteria indirectly after the pathogens cause stress within the cells.

Pictured: Pseudomonas aeruginosa
DNA wrapped around histones
What Is Epigenetics?

Physician-scientist Omar Abdel-Wahab explains epigenetics, a growing field based on the study of genetic changes that are not part of the DNA code, and how it relates to cancer.

DNA wrapped around histones
Pictured: Scott Lowe
Researchers Uncover Potential Target for “Undruggable” Form of Liver Cancer

In taking a new approach to finding treatments for hepatocellular carcinoma, MSK scientists have uncovered a potential drug target for this highly aggressive cancer.

Pictured: Scott Lowe
Pictured: Experimental Brain Tumor
Genetic “Kill Switch” Could Make Cell Therapies Safer

Researchers have engineered a gene into therapeutic cells that allows them to turn off tumor growth if some of the cells become cancerous.

Pictured: Nematode Worm Embryo
How to Build a Worm, in 3-D High Definition

Stunning movies captured in the lab of computational biologist Zhirong Bao reveal how cells divide, grow, and move around, as in a carefully choreographed dance, during the development of a nematode worm embryo.

Pictured: Nematode Worm Embryo
Soy Consumption May Promote Overexpression of Breast Cancer Genes in Some Women

Researchers have found that in a subset of women, consumption of soy could boost the expression of genes linked to breast cancer.

Prostate Cancer Organoids Provide New Tool for Evaluating Therapies

Researchers have created tiny structures called organoids from patients’ prostate tumors. These organoids will allow the study of tumors in greater detail and enable correlation of genetic mutations with drug response.

Pictured: Johanna Joyce
Researchers Find Clues to How Breast Cancer Can Infiltrate the Brain

A new study sheds light on what enables breast cancer cells to spread to the brain and presents a potential target for drugs.

Pictured: Johanna Joyce
Tumor DNA in Bloodstream May Yield New Cancer Insights

Experimental pathologist Jorge Reis-Filho explains how tumor DNA obtained from the blood could lead to noninvasive — yet highly sensitive — ways of detecting and monitoring cancer in the body.

Lab mouse with cultured human pluripotent stem cells
A New Mouse? Genetically Pliable Stem Cells Could Advance Research on Many Diseases

Memorial Sloan Kettering researchers have developed a powerful new way to study human disease using stem cells whose genomes can be manipulated at will.

Lab mouse with cultured human pluripotent stem cells