Tangible Material: SK-JHRCC-92 : Human Renal Cancer Cell Line

SK-JHRCC-92

 

Description

SK-JHRCC-92 is a human clear cell renal cell carcinoma (ccRCC) cell line that displays epithelial morphology and grows in adherent culture. This cell line forms big colonies when plated in soft agar. The SK-JHRCC-92 cells are a useful preclinical model to study renal cancer. They form tumors when inoculated subcutaneously in immunocompromised NSG mice. These xenografts are insensitive to Sunitinib (oral, small molecule, multi-targeted receptor tyrosine kinase inhibitor, approved for the treatment of renal cell carcinoma) in vivo.

Source

This cell line was established in 2012 from a metastatic site (bone) in a 45-year-old Caucasian male with clear cell carcinoma of the kidney.

Inventors

  • James J. Hsieh, MD, PhD, Laboratory Head, Memorial Hospital Research Laboratories, Human Oncology & Pathogenesis Program, Memorial Sloan Kettering Cancer Center
  • Emily H. Cheng, MD, PhD, Laboratory Head, Memorial Hospital Research Laboratories, Human Oncology & Pathogenesis Program, Memorial Sloan Kettering Cancer Center
  • Yiyu Dong, PhD, Research Associate, Hsieh Laboratory, Memorial Hospital Research Laboratories, Human Oncology & Pathogenesis Program, Memorial Sloan Kettering Cancer Center

Licensing Information

This cell line may be licensed nonexclusively for research or commercial purposes.

Contact Information

Tingting Zhang-Kharas, PhD
Licensing Assistant
Tel: 646-888-1083; Fax: 646-888-1120

E-mail: zhangkht@mskcc.org

Stage of Development
Ready to use
Technology Types