As the result of a unique interdisciplinary collaboration between physicians and scientists at Memorial Sloan Kettering and Cornell University, the Artemis Fluorescence Camera System has been introduced. It is the only camera of its kind being used in operating rooms in the United States today.
In this video, experts discuss the power and potential of the nanotechnology-based optical imaging system from Quest Medical Imaging (BV, Middenmeer, Netherlands). By coupling a handheld camera with US Food and Drug Administration IND-approved fluorescent silica nanoparticles, this system allows surgeons to visualize and treat sites of cancer metastasis in real time.
Diagnostic radiologist Michelle Bradbury, a member of Memorial Sloan Kettering’s Neuroradiology Service and Molecular Pharmacology and Chemistry Program, is co-developing these technologies with Cornell University experts. She notes that the unique combination may well represent a paradigm shift in intraoperative cancer care, as it offers visualization tools to enable increased accuracy, more-precise disease staging, and improved clinical outcomes.
Chair of Surgery Peter Scardino says the camera has the potential to aid physicians in the more than 20,000 cancer operations done at institutions such as Memorial Sloan Kettering every year. The camera gives surgeons a tool to gauge the full extent of a patient’s disease by collecting light emitted by lymph nodes that take up fluorescent particles or other dye-containing agents.
At present, the system is being used to detect and treat metastatic disease in open surgical or laparoscopic procedures. Future applications might include combining it with minimally invasive robotic systems, says Department of Radiology Chair Hedvig Hricak — leading to image-guided surgeries that are even more precise. Cornell University professor of engineering Ulrich Wiesner talks about the potential of the Artemis camera for further refining the tools used in the fight against cancer.
Memorial Sloan Kettering surgeons, including head and neck surgeon Snehal Patel, describe using the system to help identify diseased nodes for a range of tumor types. Along with Dr. Bradbury, Dr. Patel demonstrates the technology in action, describing how it helps in visualizing areas of a patient’s anatomy currently unreachable by other methods and showing how it can be applied in sentinel lymph node mapping of a facial melanoma.