On Cancer: Discoveries & Advances

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Finding

Study Reveals a New Way That Stress and Aging Lead to Alzheimer’s

A targeted approach being developed to treat certain cancers may also be effective for Alzheimer’s disease.

An illustration of a magnifying glass over a brain.

Feature

Researchers Find that Vitamin B6 Contributes to Survival of Acute Myeloid Leukemia Cells

This research marks the first time researchers have found a connection between vitamin B6 and cancer.

Cancer biologist Scott Lowe at a white board

In the Lab

What Does Cancer Metastasis Have to Do with Wound Healing? More than You Might Think

Scientists are learning that — in a literal sense — metastasis is wound healing gone wrong.

Graphical representation of cells leaking into bloodstream

In the Lab

Mind the Gap: Scientists Learn How Cells Make and Repair Tight Connections

New findings from researchers at the Sloan Kettering Institute provide insight into a fundamental biological process called the epithelial-mesenchymal transition.

Epithelial cells

In the Lab

Why KRAS Inhibitors for Lung Cancer Stop Working (and What Can Be Done about It)

Recently developed targeted drugs used to treat lung cancer are only partially effective. Scientists now know why.

A picture of KRAS-mutated lung cancer cells

In the News

10 Remarkable Basic Science Breakthroughs from 2019

As 2019 comes to an end, take a moment to reflect on the science stories that made the year one to remember.

a design of colored lines and dots

In the Lab

Neuroblastoma May Result from DNA Circles Wreaking Havoc on the Genome

Mysterious circular DNA may contribute to neuroblastoma and other childhood cancers.

Enlarged image of neuroblastoma cell with stains.

In the News

Year in Review: 10 Important Clinical Research Discoveries in 2019

As we approach the end of 2019, learn about some of the biggest advances in clinical research made this year at MSK.

Memorial Sloan Kettering medical oncologist Eileen O’Reilly

In the Clinic

Targeted Drug Shows Promise Against HER2-Positive Breast Cancer That Stops Responding to Other Drugs

MSK medical oncologist Shanu Modi is the lead author of a new paper detailing the results from a phase II trial of a breast cancer drug called trastuzumab deruxtecan or DS-8201a. Results from this study were also presented at the San Antonio Breast Cancer Symposium.

Illustration of breast cancer cell