On Cancer: Epigenetics

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28 Blog posts found

Announcement

FDA Approves Ivosidenib (Tibsovo®), a Targeted Drug, for Acute Myeloid Leukemia

The drug provides a new treatment option for people whose cancer has stopped responding to other therapies.

Hematologic oncologist Martin Tallman and nurse practitioner Bernadette Cuello

Feature

What Is Epigenetics, and Why Is Everyone Talking about It?

Epigenetics is frequently in the news, but there's lots of confusion about just what it entails.

A calico cat

In Brief

Scientists Identify How Gene Mutation Drives a Deadly Childhood Cancer

Synovial sarcoma is an aggressive cancer primarily affecting children and young adults. A new study gets to the bottom of it.

Illustration of girl standing in front of charging bull

Announcement

Three Investigators Named Winners of the 2017 Paul Marks Prize for Cancer Research

Memorial Sloan Kettering has named three winners of this year’s Paul Marks Prize for Cancer Research, an award that recognizes promising early-career investigators.

Aviv Regev of the Broad Institute and the Massachusetts Institute of Technology

Feature

The Man behind the Prize: How Paul Marks Shaped Modern Cancer Research

Recent advances in epigenetic and targeted therapies owe a lot to the foresight of former MSK President Paul Marks, who believed in the importance of basic research.

Former MSK president Paul Marks

Announcement

FDA Approves Enasidenib (Idhifa), a First-of-Its-Kind Drug, for Advanced Blood Cancer

A new treatment option for people with acute myeloid leukemia is available, and it works in an unconventional way.

Acute myeloid leukemia cells under a microscope

In the Lab

When Loss Is a Gain: New Tumor Suppressor Gene Identified in Follicular Lymphoma

The reason certain patients with follicular lymphoma do worse than others may come down to a missing gene.

A scientist looks at illustrations of chromosomes.

In the Lab

Why Immune Cells Sometimes Fail to Fight Cancer (and What to Do about It)

By looking at how DNA is packaged in cells, scientists are teasing apart a long-standing conundrum about the immune response to cancer.

Scientists at the Sloan Kettering Institute are learning why some immune cells are stubbornly hard to revive with immunotherapy.

Finding

A Missing Link Revealed: Researchers Gain Insight into Breast Cancer Drug Resistance

Researchers find an epigenetic role in how breast cancer tumors develop resistance to treatment.

Illustration of breast encompassing blue normal cells and red cancer cells.

In the Lab

Scientists Home in on Treatment Advance for Chemotherapy-Resistant Small Cell Lung Cancer

An epigenetic mechanism may make small cell lung cancer vulnerable to a new kind of attack.

MSK scientists Charles Rudin and John Poirier