On Cancer: Metastasis & Drug Resistance

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32 Blog posts found

Finding

Large Study Pinpoints Genetic Changes Underlying Drug Resistance in the Most Common Type of Breast Cancer

Scientists are learning how estrogen receptor-positive breast cancer evolves to thwart hormonal therapies and are developing ways to stop it.

Colored dots (cells) separating through a funnel-like structure.

In the Lab

Studying a Forerunner of Pancreatic Cancer Reveals New Clues about How the Disease Develops

This research is important for developing better drugs and screening methods for pancreatic tumors.

Pancreatic tumor cells

In the Lab

Scientists Identify Growth Signal for Metastatic Cancer "Seeds"

Targeting this signal with drugs might be one way to stop cancers from spreading.

This image shows cancer cells (white) and pericytes (green) clinging to capillaries (red). The blue dots are nuclei.

Q & A

Reality Check: Study Examines Metastasis after Breast Cancer Surgery

Breast cancer expert Larry Norton says laboratory study in mice shouldn’t affect how people with breast cancer are treated.

Microscopic view of a breast cancer cell

In the Lab

Escape Artists: Cancer Cells Mimic Immune Cell Activity to Spread

Researchers have discovered that cancer cells may hijack an immune response to spread from a primary tumor to distant organs.

Illustration of cells with blue nuclei that have green DNA bits floating in the cytoplasm

In the Lab

When Cancer Spreads: Research Focuses on Better Ways to Treat Metastasis

MSK investigators are learning how cancer cells escape from the original tumor and hide out in the body. Their goal is to prevent metastatic tumors from forming.

Sloan Kettering Institute Director Joan Massagué with laboratory member Karuna Ganesh

Q & A

What Evolution Can Tell Us about How Cancer Spreads

Meet Christine Iacobuzio-Donahue, a physician-scientist who studies cancer metastasis and is collaborating on genetics research with scientists at the American Museum of Natural History.

MSK pathologist Christine Iacobuzio-Donahue

In the Lab

Research Reveals How Sleeping Cancer Cells Wake Up

MSK investigators are studying how dormant cancer cells can become reactivated after remaining hidden in the body for years.

A micrograph image of breast cancer cells.

Finding

A Missing Link Revealed: Researchers Gain Insight into Breast Cancer Drug Resistance

Researchers find an epigenetic role in how breast cancer tumors develop resistance to treatment.

Illustration of breast encompassing blue normal cells and red cancer cells.

Finding

Two Studies Shed Light on Genetics of Metastatic Pancreatic Cancer

New research of metastatic pancreatic cancer has shown that the same mutations are involved in driving both the primary tumor and the metastases.

A pancreatic cancer cell