On Cancer

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42 Blog posts found

In the News

Breast Cancer Updates: Evaluating Prostate Cancer Drugs, Developing Better Predictive Tools, and Calculating Recurrence

Welcome sign at the San Antonio Breast Cancer Symposium

In the Lab

When Cancer Spreads: Research Focuses on Better Ways to Treat Metastasis

MSK investigators are learning how cancer cells escape from the original tumor and hide out in the body. Their goal is to prevent metastatic tumors from forming.

Sloan Kettering Institute Director Joan Massagué with laboratory member Karuna Ganesh

Science Byte

Blocking Enzymes That Signal DNA Damage Could Be a Treatment Strategy for Childhood Cancers

A new strategy for treating pediatric cancers involves preventing cells from repairing their own DNA.

Graphic of shattered, red, DNA double-helix

in the Lab

Jumping Genes and the Dark Genome: MSK Researchers Gain New Insight into Childhood Cancers

Researchers have discovered a genetic mechanism that may trigger most childhood cancers.

Cartoon illustration of DNA double-helix segment (with arms and legs) “jumping” to from one part of the double-helix to another.

In the Lab

Reaching a Milestone: Researchers Report Results of First 10,000 Patients Analyzed by MSK-IMPACT

Researchers are reporting the first results from MSK’s genomic sequencing test, which analyzes patients’ tumors and helps match them to the best treatment.

Test tube of blood with genetic code in the background

Finding

Looking Beyond DNA Defects to Characterize Cancer

Technologies that look only at mutations in DNA may miss other kinds of defects that can occur in cancer cells.

Melanoma cell

In the Lab

Researchers Find Potential Achilles’ Heel for Prostate Cancer and B Cell Lymphoma

Genetic molecules called microRNAs can regulate hundreds of genes. Targeting one microRNA could potentially slow the growth of two forms of cancer.

Laboratory setting, with computer screen of scientific data, beaker, and microscope.

In the Lab

Manipulating a Single Gene Turns Colorectal Cancer Cells Back to Normal

For the first time, scientists have shown that the gene APC, which is mutated in the vast majority of colorectal cancers, might be a promising target for future therapies.

Organoid cell structures fluorescing in blue, green, and purple.

In the Lab

Uncharted Waters: The Making of a New Cancer Drug

A team of scientists is combining sophisticated chemistry and experiments in zebrafish to develop a new cancer drug that shows early potential against melanoma and metastatic breast cancer.

Portrait of a live zebrafish with dark patterning around and above the eyes

In the Lab

Outsmarting Cancer’s Survival Skills

A new study led by MSK investigators reveals how some cancer cells become resistant to targeted treatment and suggests what might be done to stop that from happening.

MSK investigators Joan Massagué and Anna Obenauf