On Cancer

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45 Blog posts found

In the Lab

A Study of Rare Tumors Uncovers the Presence of Tumor-Suppressing Genes

Studying the genes of granular cell tumors has revealed a previously unknown process through which cells can turn cancerous.

Black-and-white microscopic image of cell from human granular cell tumor

Finding

Genomic Marker Is Associated with Lynch Syndrome, a Hereditary Cancer Condition, Across Many Different Cancers

Tumors with a biomarker called high microsatellite instability have been linked to inherited cancer mutations.

Zsofia Stadler presents at the ASCO meeting

Roundup

Highlights from MSK at the 2018 American Association for Cancer Research Meeting

Read up on the latest developments in several key areas of cancer research, including genomic mapping, disease modeling through CRISPR, CAR T therapy, and cancer stem cells.

Sign for AACR scientific meeting featuring collage of images

In the Lab

When Cancer Spreads: Research Focuses on Better Ways to Treat Metastasis

MSK investigators are learning how cancer cells escape from the original tumor and hide out in the body. Their goal is to prevent metastatic tumors from forming.

Sloan Kettering Institute Director Joan Massagué with laboratory member Karuna Ganesh

Science Byte

Blocking Enzymes That Signal DNA Damage Could Be a Treatment Strategy for Childhood Cancers

A new strategy for treating pediatric cancers involves preventing cells from repairing their own DNA.

Graphic of shattered, red, DNA double-helix

in the Lab

Jumping Genes and the Dark Genome: MSK Researchers Gain New Insight into Childhood Cancers

Researchers have discovered a genetic mechanism that may trigger most childhood cancers.

Cartoon illustration of DNA double-helix segment (with arms and legs) “jumping” to from one part of the double-helix to another.

In the Lab

Reaching a Milestone: Researchers Report Results of First 10,000 Patients Analyzed by MSK-IMPACT

Researchers are reporting the first results from MSK’s genomic sequencing test, which analyzes patients’ tumors and helps match them to the best treatment.

Test tube of blood with genetic code in the background

Finding

Looking Beyond DNA Defects to Characterize Cancer

Technologies that look only at mutations in DNA may miss other kinds of defects that can occur in cancer cells.

Melanoma cell

In the Lab

Researchers Find Potential Achilles’ Heel for Prostate Cancer and B Cell Lymphoma

Genetic molecules called microRNAs can regulate hundreds of genes. Targeting one microRNA could potentially slow the growth of two forms of cancer.

Laboratory setting, with computer screen of scientific data, beaker, and microscope.