On Cancer

and/or

51 Blog posts found

In the Clinic

Longest-Running CAR T Trial Shows Which Patients Benefit Most, Have Fewest Side Effects

For adults with chemotherapy-resistant leukemia, CAR T cell therapy can be a lifesaving treatment option. New results suggest how to make it safer.

Medical oncologist Jae Park

In the Lab

New Hope for Repairing a Damaged or Aging Immune System

Scientists have uncovered a molecule that, in mice, can promote the regeneration of the thymus, where T cells develop.

Three-dimensional reconstruction of the blood vessels in a mouse thymus using light-sheet fluorescent microscopy

Finding

Why Do Some People Beat the Odds against Pancreatic Cancer?

Scientists think they now understand why some people with pancreatic cancer survive for many years. Hint: It involves the immune system.

An illustration of the human pancreas

In the Lab

Why Do Immune Checkpoint Inhibitors Work for Only Some People with Cancer?

Learn about why checkpoint inhibitors, a class of immunotherapy drugs, 
is paying off — but only for some patients.

MSK physician­scientist Luis Diaz

In the Clinic

The Science Behind the FDA’s Approval of an Immunotherapy for Mismatch Repair–Deficient Cancers

A new paper from MSK physician-scientist Luis Diaz presents the evidence on which the FDA approved the immunotherapy drug pembrolizumab for cancers with a specific genetic abnormality.

MSK medical oncologist Luis Diaz, Jr.

In the Lab

Why Immune Cells Sometimes Fail to Fight Cancer (and What to Do about It)

By looking at how DNA is packaged in cells, scientists are teasing apart a long-standing conundrum about the immune response to cancer.

Finding

Blood Will Tell: Scientists Find Clues to Immunotherapy Responders and Non-Responders

Why do some patients respond to immunotherapy while others do not? Blood may hold the answer.

photo of blood vials

Finding

New Data Show Some Patients with Melanoma Live Longer When Receiving Immunotherapy Combination

For some patients with metastatic melanoma, a combination of two immunotherapies works better than either drug alone.

Feature

T Is for T Cell: The Science Behind Immunotherapy

By deciphering the biology of T cells, MSK scientists gave immunotherapy a boost.

T cells on the loose.

Q&A

New Approach Could Boost Immunotherapy for Breast Cancer

A protein on certain immune cells is a promising target for making immunotherapy more effective against breast cancer.

Illustration of immune cell opening as if on hinge and boxing glove coming out.