On Cancer

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52 Blog posts found

In the Lab

New Hope for Repairing a Damaged or Aging Immune System

Scientists have uncovered a molecule that, in mice, can promote the regeneration of the thymus, where T cells develop.

Three-dimensional reconstruction of the blood vessels in a mouse thymus using light-sheet fluorescent microscopy

In the Lab

Prostate Cancer Drug Could Protect Bone Marrow from Damage Caused by Radiation

Researchers are working on a novel method for addressing a common complication of cancer treatment — bone marrow suppression.

Cross sections of mouse femurs showing bone marrow after radiation and no drug (left) and after radiation plus drug (right).

Q & A

Study Uncovers Genetic Reasons Why Some People Respond to Immunotherapy Better than Others

Immunotherapy drugs called checkpoint inhibitors have been a game changer for some people with cancer. But for most patients, these drugs have been disappointing. Researchers are trying to figure out why.

Model of a T cell receptor and an HLA-A white blood cell antigen bound to part of a virus

In the Lab

When Cancer Spreads: Research Focuses on Better Ways to Treat Metastasis

MSK investigators are learning how cancer cells escape from the original tumor and hide out in the body. Their goal is to prevent metastatic tumors from forming.

Sloan Kettering Institute Director Joan Massagué with laboratory member Karuna Ganesh

Finding

Why Do Some People Beat the Odds against Pancreatic Cancer?

Scientists think they now understand why some people with pancreatic cancer survive for many years. Hint: It involves the immune system.

An illustration of the human pancreas

Science Byte

Insight into How Lungs Repel Infection Could Guide Therapies for Transplant Patients

Learn how immune cells in the lungs trigger invasive fungal cells to self-destruct. The discovery could produce therapies to prevent infection in cancer patients.

Petri dish with green mold on it

Finding

Is Neurodegenerative Disease a Kind of Cancer?

New findings from experiments done in mice suggest a surprising cause of common neurodegenerative diseases such as Alzheimer’s and Parkinson’s.

A network of neurons

In the Lab

Why Immune Cells Sometimes Fail to Fight Cancer (and What to Do about It)

By looking at how DNA is packaged in cells, scientists are teasing apart a long-standing conundrum about the immune response to cancer.

Scientists at the Sloan Kettering Institute are learning why some immune cells are stubbornly hard to revive with immunotherapy.

In the Lab

CRISPR Genome-Editing Tool Takes Cancer Immunotherapy to the Next Level

What do you get when you combine two of the hottest areas of biotechnology? A new paper from MSK researchers explains.

CAR T cells attacking cancer