The Impact of Androgen Ablation Therapy on Cognitive Functioning and Functional Status in Men with Prostate Cancer Age 65 and Older

Full Title

The Impact of Androgen Ablation Therapy on Cognitive Functioning and Functional Status in Men with Prostate Cancer Age 65 and Older

Purpose

Androgen ablation therapy is a type of hormonal therapy used to treat men with advanced prostate cancer. In this study, researchers want to determine if the drugs Lupron, Casodex, and Zolodex cause changes in functions such as memory, learning, or concentration (“cognitive functions”). The results of this study will be used in the future to help other men with prostate cancer who may need hormonal treatment with these drugs.

The study will include two groups of men with prostate cancer who are age 65 and older: one group of men who are receiving or will receive hormonal therapy, and one group which will not receive hormonal therapy. Participants will be asked to complete several questionnaires that focus on thinking ability, depression, anxiety, fatigue, and pain. They will complete these surveys at the beginning of the study and then again one year later. Researchers will compare the findings between the two groups.

Eligibility

To be eligible for this study, patients must meet several criteria, including but not limited to the following:

  • Participants must be men age 65 or older with prostate cancer.
  • Participants must be fluent in English.

For more information about this study, please contact Dr. Christian Nelson at 646-888-0030.

Protocol

06-084

Investigator

Locations